Results 11 to 20 of about 86,485 (257)

Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study [PDF]

RMD Open, 2023
Objectives In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients.Methods We conducted a retrospective multicentre study in referral centres ...
Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo   +56 more
doaj   +2 more sources

The impact of tocilizumab on physical function and quality of life in patients with rheumatoid arthritis: a systematic literature review and interpretation

Open Access Rheumatology: Research and Reviews, 2012
Shatara V Townes,1 Daniel E Furst,1 Anuradha Thenkondar21Department of Rheumatology, University of California-Los Angeles, Los Angeles, CA, USA; 2Sri Ramachandra Medical College and Research Institute, Chennai, IndiaObjective: To determine the impact of ...
Townes SV, Furst DE, Thenkondar A
doaj   +1 more source

Comment on: Benchmarking tocilizumab use for giant cell arteritis [PDF]

, 2022
It is with great interest we read the editorial on tocilizumab (TCZ) use in giant cell arteritis (GCA) published on 9th May, 2022 by Conway et al [1]. We write to share some of our data to add weight to the views expressed, particularly in relation to ...
Robson, Joanna C, Janagan, Shalini, Skeoch, Sarah, Guly, Catherine   +3 more
core   +1 more source

Therapeutic effectiveness of tocilizumab in the treatment of cytokine release syndrome in patients with COVID-19 [PDF]

, 2021
Introducción: tocilizumab, fue aprobado en el 2017 por la Food and Drugs Administration para el tratamiento del síndrome de liberación de citoquinas, por lo que se ha empleado en la terapéutica de pacientes graves por SARS-CoV 2.
Denis-Piedra, Daniel Alejandro, Isla Alfonso, David, Jiménez Puentes, Mónica   +2 more
core   +1 more source

Tocilizumab Reduces Vasospasms, Neuronal Cell Death, and Microclot Formation in a Rabbit Model of Subarachnoid Hemorrhage. [PDF]

, 2021
Early brain injury (EBI), delayed cerebral vasospasm (DCVS), and delayed cerebral ischemia (DCI) are common complications of subarachnoid hemorrhage (SAH).
Marbacher, Serge, von Gunten, Michael, Widmer, Hans Rudolf, Casoni, Daniela, Grüter, Basil E, Sivanrupan, Sivani, Andereggen, Lukas, Strange, Fabio, Mariani, Luigi, Croci, Davide M, Fandino, Javier, Di Santo, Stefano, Wanderer, Stefan   +12 more
core   +1 more source

Early use of low dose tocilizumab in patients with COVID-19: A retrospective cohort study with a complete follow-up

EClinicalMedicine, 2020
Background: Pneumonia with severe respiratory failure represents the principal cause of death in COVID-19, where hyper-inflammation plays an important role in lung damage.
Nicola De Rossi, Cristina Scarpazza, Chiara Filippini, Cinzia Cordioli, Sarah Rasia, Chiara Rosa Mancinelli, Damiano Rizzoni, Giuseppe Romanelli, Stefania Cossi, Nereo Vettoretto, Sergio Bove, Silvano Manfredini, Eva Andrea Beindorf, Carlo Mosca, Vittorio Scipione, Gigliola Flamminio, Elena Albini Albini, Paola Giansiracusa, Ruggero Capra   +18 more
doaj   +1 more source

Factors Influencing Disease Stability and Response to Tocilizumab Therapy in Severe COVID-19: A Retrospective Cohort Study

Antibiotics, 2022
(1) Background: The efficacy of tocilizumab in COVID-19 has been doubted. The study aimed to investigate factors affecting disease stability and response to tocilizumab among severe COVID-19 patients.
Wael Hafez, Ahmed Abdelrahman
doaj   +1 more source

Tocilizumab Is Associated with Increased Risk of Fungal Infections among Critically Ill Patients with COVID-19 and Acute Renal Failure: An Observational Cohort Study

Life, 2023
Research Question: Does treatment with tocilizumab increase the risk of a fungal infection in critically ill patients with coronavirus-19? Background: Numerous therapies have been evaluated as possible treatments for coronavirus-2019 caused by severe ...
Barrett J. Burger, Sarenthia M. Epps, Victor M. Cardenas, Rajani Jagana, Nikhil K. Meena, William T. Atchley   +5 more
doaj   +1 more source

First Report of Tocilizumab Use in a Cohort of Latin American Patients Hospitalized for Severe COVID-19 Pneumonia

Frontiers in Medicine, 2020
Introduction/objectives: An interleukin-6 inhibition strategy could be effective in selected COVID-19 patients. The objective is to present our experience of tocilizumab use in patients with severe COVID-19.Methods: Observational retrospective cohort ...
Omar Valenzuela, Omar Valenzuela, Sebastián Ibáñez, Sebastián Ibáñez, M. Cecilia Poli, M. Cecilia Poli, M. Cecilia Poli, Patricia Roessler, Patricia Roessler, Mabel Aylwin, Mabel Aylwin, Gigia Roizen, Gigia Roizen, Mirentxu Iruretagoyena, Mirentxu Iruretagoyena, Vivianne Agar, Vivianne Agar, Javiera Donoso, Javiera Donoso, Margarita Fierro, Margarita Fierro, José Montes, José Montes   +22 more
doaj   +1 more source

Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation

Frontiers in Genetics, 2021
COVID-19 has posed a significant threat to global health. Early data has revealed that IL-6, a key regulatory cytokine, plays an important role in the cytokine storm of COVID-19.
Arya Zarinsefat, George Hartoularos, Dmitry Rychkov, Priyanka Rashmi, Sindhu Chandran, Flavio Vincenti, Chun J. Yee, Minnie M. Sarwal   +7 more
doaj   +1 more source