Results 31 to 40 of about 86,485 (257)

A comparison of the effectiveness of different doses of tocilizumab and sarilumab in the treatment of severe COVID-19: a natural experiment due to drug shortages

open access: yesInternational Journal of Infectious Diseases, 2023
Objectives: Interleukin (IL)-6 inhibitors are administered to treat patients hospitalized with COVID-19. In 2021, due to shortages, different dosing regimens of tocilizumab, and a switch to sarilumab, were consecutively implemented. Using real-world data,
Maaike C. Swets   +12 more
doaj   +1 more source

CU Tocilizumab Colombia

open access: yes, 2022
CU Tocilizumab ...
Jefferson Buendia
core   +1 more source

Case Report: Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C

open access: yesCase Reports in Medicine, 2012
Tocilizumab is a monoclonal humanized anti-IL-6-receptor antibody used for the treatment of rheumatoid arthritis. The safety of tocilizumab in HCV patients is an open question. We report on safety and efficacy of tocilizumab in a 71-year-old female with
Filippo Iebba   +5 more
doaj   +1 more source

Comparison of the inhibitory effect of tocilizumab and etanercept on the progression of joint erosion in rheumatoid arthritis treatment

open access: yesScientific Reports, 2022
We compared the efficacy of tocilizumab and etanercept in inhibiting radiographic progression of joint destruction in rheumatoid arthritis. Overall, 187 patients treated with etanercept or tocilizumab were selected.
Shinya Hayashi   +11 more
doaj   +1 more source

Effectiveness and safety of tocilizumab in patients with systemic sclerosis: a propensity score matched controlled observational study of the EUSTAR cohort

open access: yesRMD Open, 2022
Objectives Tocilizumab showed trends for improving skin fibrosis and prevented progression of lung fibrosis in systemic sclerosis (SSc) in randomised controlled clinical trials.
  +106 more
doaj   +1 more source

Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions

open access: yes, 2011
Mahmud Mahamid1,3, Reuven Mader4, Rifaat Safadi1,2 1Liver Unit, Holy Family Hospital, Nazareth, Israel; 2Hadassah Medical Center, Jerusalem, Israel; 3Shaare Zedek Medical Center, Jerusalem, Israel; 4Rheumatology Unit, Ha’emek Medical Center ...
Safadi R   +5 more
core   +1 more source

Tocilizumab treatment for COVID-19 patients: a systematic review and meta-analysis

open access: yesInfectious Diseases of Poverty, 2021
Background Coronavirus disease 2019 (COVID-19) has killed over 2.5 million people worldwide, but effective care and therapy have yet to be discovered. We conducted this analysis to better understand tocilizumab treatment for COVID-19 patients.
Qiu Wei   +6 more
doaj   +1 more source

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

open access: yesAnnals of Clinical and Translational Neurology
Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels.
Yushan He   +7 more
doaj   +1 more source

Tocilizumab promotes corneal allograft survival in rats by modulating Treg-Th17 balance [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To examine the therapeutic effects of tocilizumab on experimental corneal transplantation and its effect on Treg/Th17 balance. METHODS: Allograft corneal graft was performed between host Sprague Dawley and Wistar donor rats.
Xiao-Song Wu   +5 more
doaj   +1 more source

Secondary Infection and Co-infection in COVID-19 Patients Receiving Tocilizumab [PDF]

open access: yes
Objective: Tocilizumab (TCZ) is a recombinant humanized anti-IL-6 receptor monoclonal antibody that is beneficial in critically ill COVID-19 patients. However, the clinical efficacy and safety of immunosuppressants (including tocilizumab, sarilumab and ...
Hülya Sungurtekin   +3 more
core   +1 more source

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