Thymol and Carvacrol as Potential Tocolytic and Anti-inflammatory Agents in Pregnant Rat Uterus
Current Molecular PharmacologyINTRODUCTION This work aimed to evaluate the anti-inflammatory and myorelaxant effect of thymol (TM) and carvacrol (CAR) in the pregnant rat uterus. Both compounds exhibit considerable antimicrobial, antispasmodic, and anti-inflammatory effects and due ...
Víctor Manuel Muñóz-Pérez +3 more
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Balkan Medical JournalBackground Cesarean section is frequently performed for breech presentation; however, external cephalic version (ECV) is recommended as an alternative strategy to increase the likelihood of vaginal birth.
Yunyun Xiao, Jinhe Shi, Yan Dong, Lu Han
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A comparative study on MgSO₄ and nifedipine as acute tocolytic agent in preterm labour
International Journal of Reproduction Contraception Obstetrics and GynecologyBackground: Preterm labour is a major cause of neonatal morbidity and mortality. Tocolysis helps delay delivery, allowing time for antenatal corticosteroids and in-utero transfer.
Neethika Raghuwanshi +2 more
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Comparative effectiveness and safety of nifedipine and magnesium sulfate as treatment options for preterm birth: a systematic review and meta-analysis [PDF]
BMJ OpenObjectives Preterm birth (PTB) is a major cause of neonatal morbidity and mortality worldwide. Effective use of tocolytic agents may improve perinatal outcomes.
Jie Chen +7 more
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Human Chorionic Gonadotropin vs. Magnesium Sulfate (MgSO4) as a Tocolytic Agent: A Randomized Controlled Trial. [PDF]
CureusMushtaq HF +4 more
europepmc +3 more sources
Synergistic effects of nifedipine and indomethacin in tocolysis: A translational study. [PDF]
Int J Gynaecol ObstetInternational Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 1418-1420, December 2025.
Yart L, Cohen M, Martinez de Tejada B.
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School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12-Year Follow-Up of the APOSTEL 2 Trial. [PDF]
BJOGABSTRACT Objective To evaluate school performance at 12 years of age in children prenatally exposed to maintenance tocolysis with nifedipine versus placebo. Design 12‐year follow‐up of the multicentre APOSTEL 2 trial, in which participants with threatened preterm birth between 26+0 and 32+2 weeks of gestation, who remained pregnant after initial 48‐h ...
van der Windt LI +8 more
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Evaluation of transdermal nitroglycerine as tocolytic agent in preterm labour
International journal of health sciences, 2022 Background: Preterm birth continues to be a problem for obstetricians. Preterm birth complicates 8-10% of birth. Although the causes of preterm labor are not well understood, the burden of preterm birth is clear. Aim and objectives: The aim was to study to evaluate the efficacy and safety of transdermal nitroglycerin as tocolytic agent in women with ...
Fahd Abd Alaal Alomda +2 more
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Efficacy of oral nifedipine as a tocolytic agent
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2021 Background: Preterm birth is defined as birth at less than 37 weeks period of gestation, is the most important single determinant of adverse infant outcome in terms of both survival and quality of life. The need for tocolysis in terms of safety and efficacy is necessary to decrease perinatal mortality and morbidity in preterm labour.
Veena Bikkolli Teekappa Gowda +1 more
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BMC Pregnancy and Childbirth, 2022 Background A few studies have reported that maternal administration of antenatal corticosteroids increased the risk of pulmonary edema (PE). However, despite the increasing usage rate of betamethasone as antenatal corticosteroid, maternal administration ...
Takashi Nishikawa, Ken Fukuhara
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