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Antiproliferative Activity of α-Tocopherol, γ-Tocopherol and Tocotrienols and Their Drug Interactions Evaluated Using Loewe and Chou-Talalay Models in HeLa and MCF-7 Cancer Cell Lines. [PDF]

Biomedicines
Stevens Barron JC, de la Rosa LA, Alvarez-Parrilla E, Wall-Medrano A, Chapa González C.   +4 more
europepmc   +1 more source

Complexation of Tocotrienol with γ-Cyclodextrin Enhances Intestinal Absorption of Tocotrienol in Rats

Bioscience, Biotechnology and Biochemistry, 2010
To determine the bioavailability of tocotrienol complex with gamma-cyclodextrin, the effects of tocotrienol/gamma-cyclodextrin complex on tocotrienol concentration in rat plasma and tissues were studied. Rats were administered by oral gavage an emulsion containing tocotrienol, tocotrienol with gamma-cyclodextrin, or tocotrienol/gamma-cyclodextrin ...
Tomohiro Yano, Tomono Uchida, Daisuke Nakata   +2 more
exaly   +3 more sources

γ-Tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways

British Journal of Cancer, 2008
Tocotrienol-rich fraction (TRF) has demonstrated antiproliferative effect on prostate cancer (PCa) cells. To elucidate this anticancer property in PCa cells, this study aimed, first, to identify the most potent isomer for eliminating PCa cells; and ...
Wong Y C
exaly   +2 more sources

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Tocotrienols

2008
Introduction and Overview Tocotrienols: A Review, A.G. Schauss Tocotrienols in Vitamin E: Hype or Science?, N.E. Levin and D.L. Clouatre Sources Tocotrienols: Distribution and Sources Cereals-Role in Human Health, H. Zielinski Tocotrienols in Plants: Sources and Importance, L. Harinantenaina Vitamin E: Natural vs. Synthetic, A.
  +4 more sources

Tocotrienols in Cardioprotection

2007
Tocotrienols, a group of Vitamin E stereoisomers, offer many health benefits including their ability to lower cholesterol levels, and provide anticancer and tumor-suppressive activities. Several recent studies determined the cardioprotective abilities of tocotrienols, although the number is only 1% compared to the study with tocopherols.
Samarjit, Das, Kalanithi, Nesaretnam, Dipak K, Das   +2 more
openaire   +3 more sources

Tocotrienol and cancer metastasis

BioFactors, 2016
AbstractTumor metastasis involves some of the most complex and dynamic processes in cancer, often leading to poor quality of life and inevitable death. The search for therapeutic compounds and treatment strategies to prevent and/or manage metastasis is the ultimate challenge to fight cancer.
Leanne, De Silva, Lay Hong, Chuah, Puvaneswari, Meganathan, Ju-Yen, Fu   +3 more
openaire   +2 more sources

Nutrapharmacology of Tocotrienols for Metabolic Syndrome

Current Pharmaceutical Design, 2011
Metabolic syndrome is defined as a set of health risk factors that are associated with an increased chance of cardiovascular diseases and type 2 diabetes. These include abdominal obesity, hyperglycemia, impaired glucose tolerance, dyslipidemia, and hypertension.
Weng-Yew, Wong, Brown, Lindsay
openaire   +5 more sources

Tocotrienols and Cardiovascular Health

Current Pharmaceutical Design, 2011
This review emphasizes the effects of tocotrienols on the risk factors for atherosclerosis, plaque instability and thrombogenesis, and compares these effects with tocopherol. Tocotrienols reduce serum lipids and raise serum HDL-C. Alpha-tocopherol, on the other hand, has no effect on serum lipids.
openaire   +2 more sources

Tocotrienol Distribution in Foods: Estimation of Daily Tocotrienol Intake of Japanese Population

Journal of Agricultural and Food Chemistry, 2010
Tocotrienol (T3) is an unsaturated form of natural vitamin E that has been focused on because of its potential health benefits (i.e., antioxidative, antihypercholesterolemic, and antiangiogenic effects). The presence of T3 in some plant sources (e.g., rice bran and palm oil) is known, but its distribution in other edible sources and its daily intake ...
Phumon, Sookwong, Kiyotaka, Nakagawa, Yasuhiro, Yamaguchi, Taiki, Miyazawa, Shunji, Kato, Fumiko, Kimura, Teruo, Miyazawa   +6 more
openaire   +2 more sources

[Progression of tocotrienols].

Wei sheng yan jiu = Journal of hygiene research, 2004
Tocotrienols is an isoform of tocopherols. Tocotrienols consists of a chromanol nucleus and a lipophilic isoprenoid chain. Tocotrienols were found in high concentrations in palm oil and rice bran. Its discovery was mainly antioxidant and resistant to lipid peroxidation.
Wenguang, Sun, Yageng, Yan, Fengli, Dong
openaire   +1 more source