Results 1 to 10 of about 66,122 (265)

Tocopherol vs. Tocopherol Acetate as a "Sparer" of Vitamin A.

open access: yesExperimental Biology and Medicine, 1949
Summary1. In bio-assays of vitamin A, α-tocopherol, but not α-tocopherol acetate, increased the rate of gain in the assay period. In a post-assay depletion period, animals that received α-tocopherol during the assay period survived 30-80% longer than controls.2.
M C, MILES, E M, ERICKSON, H A, MATTILL
openaire   +2 more sources

Oxidative stress stimulates alpha-tocopherol transfer protein in human trophoblast tumor cells BeWo [PDF]

open access: yes, 2012
alpha-Tocopherol transfer protein (alpha-TTP) has been identified as the major intracellular transport protein for the antioxidant vitamin E (alpha-Tocopherol).
Etzl, Ronny P.   +7 more
core   +1 more source

The formation of homogentisate in the biosynthesis of tocopherol and plastoquinone in spinach chloroplasts [PDF]

open access: yes, 1982
Homogentisate is the precursor in the biosynthesis of -tocopherol and plastoquinone-9 in chloroplasts. It is formed of 4-hydroxyphenylpyruvate of the shikimate pathway by the 4-hydroxyphenylpyruvate dioxygenase.
Soll, Jürgen   +5 more
core   +1 more source

Engineering of a functional γ-tocopherol transfer protein [PDF]

open access: yes, 2021
α-tocopherol transfer protein (TTP) was previously reported to self-aggregate into 24-meric spheres (α-TTPS) and to possess transcytotic potency across mono-layers of human umbilical vein endothelial cells (HUVECs).
Schneider, Gisbert   +9 more
core   +1 more source

Tocopherols in Micro-organisms [PDF]

open access: yesNature, 1959
ALTHOUGH the tocopherols, and in particular α-tocopherol, are widely distributed in Nature, they have not so far been identified in micro-organisms. The only micro-organism that has been adequately studied is bakers' yeast, which has been found to contain no tocopherol, although it contains another substance with vitamin E-like activity1.
J, GREEN, S A, PRICE, L, GARE
openaire   +2 more sources

Gene-regulatory activity of alpha-tocopherol.

open access: yes, 2010
Vitamin E is an essential vitamin and a lipid soluble antioxidant, at least, under in vitro conditions. The antioxidant properties of vitamin E are exerted through its phenolic hydroxyl group, which donates hydrogen to peroxyl radicals, resulting in ...
Lodge, John K.   +11 more
core   +1 more source

A Tomato Tocopherol Binding Protein Sheds Light on Intracellular α-tocopherol Metabolism in Plants [PDF]

open access: yes, 2018
Tocopherols are non-polar compounds synthesized in the plastids, which function as major antioxidants of the plant cells and are essential in the human diet.
Bermudez Salazar, Luisa   +32 more
core   +1 more source

Engineering tocopherol biosynthetic pathway in lettuce

open access: yes, 2011
In order to increase tocopherol content, genes encoding Arabidopsis homogentisate phytyltransferase (HPT) and γ-tocopherol methyltransferase (γ-TMT) were constitutively over-expressed in lettuce (Lactuca sativa L. var. logifolia), alone or in combination.
X. Sun   +6 more
core   +1 more source

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

open access: yesAdvanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell   +7 more
wiley   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao   +19 more
wiley   +1 more source

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