Results 1 to 10 of about 6,568 (206)

Tocotrienols exhibit superior ferroptosis inhibition over tocopherols [PDF]

Scientific Reports
Ferroptosis is a regulated form of cell death characterized by iron-dependent phospholipid peroxidation. Micronutrients play a critical role in modulating cellular sensitivity to ferroptosis, with vitamin E being a well-known ferroptosis inhibitor ...
Hao Yang, Junya Ito, Taiki Maejima, Shinnosuke Kimura, Hikaru Ino, Yusuke Hirata, Atsushi Matsuzawa, Sho Kobayashi, Eikan Mishima, Kiyotaka Nakagawa   +9 more
doaj   +2 more sources

Tocotrienols as an Anti-Breast Cancer Agent

Antioxidants, 2021
In the past few years, breast cancer has become the most prevalent type of cancer. The majority of patients receive combinatorial chemotherapy treatments, which may result in increased risk of developing drug resistance, a reduced quality of life, and ...
Madison Trujillo, Anupreet Kharbanda, Christa Corley, Pilar Simmons, Antiño R. Allen   +4 more
doaj   +2 more sources

An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial [PDF]

Frontiers in Nutrition
Background/objectivesTocotrienols are a form of vitamin E that may have neuroprotective effects. However, there have been no studies examining its effects on cognitive function when delivered as a stand-alone intervention. The purpose of this two-arm, 12-
Adrian L. Lopresti, Adrian L. Lopresti, Stephen J. Smith, Lixin Ding, Yanmei Li, Peinan Zhang   +5 more
doaj   +2 more sources

Cultivated St. John’s Wort Flower Heads Accumulate Tocotrienols over Tocopherols, Regardless of the Year of the Plant [PDF]

Plants
St. John’s wort (Hypericum perforatum L.) has been extensively utilized across various traditional medicinal systems, including ancient Greek medicine, traditional Chinese medicine, and Islamic medicine. H.
Ieva Miķelsone, Elise Sipeniece, Inga Mišina, Elvita Bondarenko, Paweł Górnaś   +4 more
doaj   +2 more sources

Protective Effects of Tocotrienols in Cerebral and Myocardial Ischemia-Reperfusion Injury: A Systematic Review

Applied Sciences, 2021
Although the current treatments for stroke and myocardial infarction contribute to an improvement in mortality rates, the consequences of reperfusion therapy have remained a challenge. Tocotrienols have been shown to exert beneficial effects on the brain
Fitri Fareez Ramli, Adli Ali, Nurul ’Izzah Ibrahim   +2 more
doaj   +1 more source

Stabilization and Release of Palm Tocotrienol Emulsion Fabricated Using pH-Sensitive Calcium Carbonate

Foods, 2021
Calcium carbonate (CaCO3) has been utilized as a pH-responsive component in various products. In this present work, palm tocotrienols-rich fraction (TRF) was successfully entrapped in a self-assembled oil-in-water (O/W) emulsion system by using CaCO3 as ...
Phui Yee Tan, Beng Ti Tey, Eng Seng Chan, Oi Ming Lai, Hon Weng Chang, Tai Boon Tan, Yuanfa Liu, Yong Wang, Chin Ping Tan   +8 more
doaj   +1 more source

Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects

Antioxidants, 2023
Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation countermeasures.
Stephen A. Shrum, Ujwani Nukala, Shivangi Shrimali, Edith Nathalie Pineda, Kimberly J. Krager, Shraddha Thakkar, Darin E. Jones, Rupak Pathak, Philip J. Breen, Nukhet Aykin-Burns, Cesar M. Compadre   +10 more
doaj   +1 more source

Effects of tocotrienols supplementation on markers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials.

PLoS ONE, 2021
Studies investigating the effects of tocotrienols on inflammation and oxidative stress have yielded inconsistent results. This systematic review and meta-analysis aimed to evaluate the effects of tocotrienols supplementation on inflammatory and oxidative
Ban-Hock Khor, Hui-Ci Tiong, Shing Cheng Tan, Sok Kuan Wong, Kok-Yong Chin, Tilakavati Karupaiah, Soelaiman Ima-Nirwana, Abdul Halim Abdul Gafor   +7 more
doaj   +1 more source

Effects of nano-emulsion preparations of tocopherols and tocotrienols on oxidative stress and osteoblast differentiation [PDF]

Archives of Biological Sciences, 2017
Tocopherols and tocotrienols are two groups of compounds in the vitamin E family, of which the tocopherols are widely used as antioxidant dietary supplements.
Song Liang-Song, Zhang Zhi-Xin, Wang Yang, Liu Yang, Zhang Rui, Lu Lai-Jin   +5 more
doaj   +1 more source

Effect of Ultrasonic Pretreatment on the Biosynthesis of Tocopherols, Tocotrienols and Carotenoids in Flax Sprouts (Linum Usitatissimum L.)

Journal of Natural Fibers, 2022
This study evaluated the effect of ultrasonic pretreatment of flaxseeds for 0–10 min on the biosynthesis of tocopherols, tocotrienols, and carotenoids in flax sprouts.
Xinbo Guo, Yixin Wu, Nan Xiang, Fangyang Gao, Caisheng Qiu   +4 more
doaj   +1 more source