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Tocotrienols exhibit superior ferroptosis inhibition over tocopherols [PDF]

open access: yesScientific Reports
Ferroptosis is a regulated form of cell death characterized by iron-dependent phospholipid peroxidation. Micronutrients play a critical role in modulating cellular sensitivity to ferroptosis, with vitamin E being a well-known ferroptosis inhibitor ...
Hao Yang   +9 more
doaj   +2 more sources

An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial [PDF]

open access: yesFrontiers in Nutrition
Background/objectivesTocotrienols are a form of vitamin E that may have neuroprotective effects. However, there have been no studies examining its effects on cognitive function when delivered as a stand-alone intervention. The purpose of this two-arm, 12-
Adrian L. Lopresti   +5 more
doaj   +2 more sources

Tocotrienols as an Anti-Breast Cancer Agent

open access: yesAntioxidants, 2021
In the past few years, breast cancer has become the most prevalent type of cancer. The majority of patients receive combinatorial chemotherapy treatments, which may result in increased risk of developing drug resistance, a reduced quality of life, and ...
Anupreet Kharbanda   +2 more
exaly   +3 more sources

Cultivated St. John’s Wort Flower Heads Accumulate Tocotrienols over Tocopherols, Regardless of the Year of the Plant [PDF]

open access: yesPlants
St. John’s wort (Hypericum perforatum L.) has been extensively utilized across various traditional medicinal systems, including ancient Greek medicine, traditional Chinese medicine, and Islamic medicine. H.
Ieva Miķelsone   +4 more
doaj   +2 more sources

Protective Effects of Tocotrienols in Cerebral and Myocardial Ischemia-Reperfusion Injury: A Systematic Review

open access: yesApplied Sciences, 2021
Although the current treatments for stroke and myocardial infarction contribute to an improvement in mortality rates, the consequences of reperfusion therapy have remained a challenge. Tocotrienols have been shown to exert beneficial effects on the brain
Fitri Fareez Ramli   +2 more
doaj   +1 more source

Stabilization and Release of Palm Tocotrienol Emulsion Fabricated Using pH-Sensitive Calcium Carbonate

open access: yesFoods, 2021
Calcium carbonate (CaCO3) has been utilized as a pH-responsive component in various products. In this present work, palm tocotrienols-rich fraction (TRF) was successfully entrapped in a self-assembled oil-in-water (O/W) emulsion system by using CaCO3 as ...
Phui Yee Tan   +8 more
doaj   +1 more source

Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects

open access: yesAntioxidants, 2023
Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation countermeasures.
Stephen A. Shrum   +10 more
doaj   +1 more source

Effects of tocotrienols supplementation on markers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials.

open access: yesPLoS ONE, 2021
Studies investigating the effects of tocotrienols on inflammation and oxidative stress have yielded inconsistent results. This systematic review and meta-analysis aimed to evaluate the effects of tocotrienols supplementation on inflammatory and oxidative
Ban-Hock Khor   +7 more
doaj   +1 more source

Tocotrienols

open access: yesThe Professional Medical Journal, 2012
Objective: To evaluate the effect of tocotrienols on intimal thickening in ascending aorta of cholesterol-fed rabbits. StudyDesign: Randomized control trial. Place and duration of study: The Anatomy department of Army Medical College, Rawalpindi, from March2009 to February 2010.
Uzma SHAHID   +2 more
  +5 more sources

Transcriptomic Analysis of the Anticancer Effects of Annatto Tocotrienol, Delta-Tocotrienol and Gamma-Tocotrienol on Chondrosarcoma Cells

open access: yesNutrients, 2022
Previous studies have demonstrated the anticancer activities of tocotrienol on several types of cancer, but its effects on chondrosarcoma have never been investigated. Therefore, this study aims to determine the anticancer properties of annatto tocotrienol (AnTT), γ-tocotrienol (γ-T3) and δ-tocotrienol (δ-T3) on human chondrosarcoma SW1353 cells ...
Kok-Lun Pang   +6 more
openaire   +2 more sources

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