Results 21 to 30 of about 6,334 (187)
Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity. [PDF]
PLoS ONE, 2012 The zinc finger antiviral protein (ZAP) is a host factor that mediates inhibition of viruses in the Filoviridae, Retroviridae and Togaviridae families.
Sophiya Karki +5 more
doaj +1 more source
A mini-review on sofosbuvir and daclatasvir treatment in coronavirus disease 2019
New Microbes and New Infections, 2021 Sofosbuvir and daclatasvir have been used successfully since 2013 for hepatitis C treatment. It has been shown by different studies that sofosbuvir can inhibit RNA polymerase of other positive-strand RNA viruses including Flaviviridae and Togaviridae ...
M. Shabani +3 more
doaj +1 more source
Complex antigen presentation pathway for an HLA-A*0201-restricted epitope from Chikungunya 6K protein. [PDF]
PLoS Neglected Tropical Diseases, 2017 The adaptive cytotoxic T lymphocyte (CTL)-mediated immune response is critical for clearance of many viral infections. These CTL recognize naturally processed short viral antigenic peptides bound to human leukocyte antigen (HLA) class I molecules on the ...
Elena Lorente +5 more
doaj +1 more source
Intervirology, 1978 The family Togaviridae is described; it contains four genera--Alphavirus, Flavivirus, Pestivirus and Rubivirus--and additional members. The main characteristics of the family are as follows: single-stranded, linear RNA, molecular weight about 4 X 10(6). Virions have isometric nucleocapsids surrounded by a lipoprotein envelope containing host cell lipid
J S, Porterfield +10 more
openaire +2 more sources
Pathogens, 2019 The mosquito-borne chikungunya virus (CHIKV) has become a major global health problem. Upon infection, chikungunya fever (CHIKF) can result in long-term joint pain and arthritis, and despite intense research, no licensed vaccine for CHIKV is available ...
Rafael Kroon Campos +5 more
doaj +1 more source
Инфекция и иммунитет, 2014 . This review summarizes data about rubella virus and its teratogenic action, congenital rubella syndrome (CRS), modern methods of diagnostics and prevention of infection.
A. J. Antipova
doaj +1 more source
Mayaro Virus in Wild Mammals, French Guiana
Emerging Infectious Diseases, 2003 A serologic survey for Mayaro virus (Alphavirus, Togaviridae) in 28 wild nonflying forest mammal species in French Guiana showed a prevalence ranging from 0% to 52% and increasing with age.
Benoît de Thoisy +4 more
doaj +1 more source
Alphavirus-Induced Membrane Rearrangements during Replication, Assembly, and Budding
Pathogens, 2021 Alphaviruses are arthropod-borne viruses mainly transmitted by hematophagous insects that cause moderate to fatal disease in humans and other animals. Currently, there are no approved vaccines or antivirals to mitigate alphavirus infections.
Zeinab Elmasri +2 more
doaj +1 more source