Results 21 to 30 of about 10,905 (230)
Complex antigen presentation pathway for an HLA-A*0201-restricted epitope from Chikungunya 6K protein. [PDF]
PLoS Neglected Tropical Diseases, 2017 The adaptive cytotoxic T lymphocyte (CTL)-mediated immune response is critical for clearance of many viral infections. These CTL recognize naturally processed short viral antigenic peptides bound to human leukocyte antigen (HLA) class I molecules on the ...
Elena Lorente +5 more
doaj +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
, 2013 The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L. +8 more
core +3 more sources
Intervirology, 1978 The family Togaviridae is described; it contains four genera--Alphavirus, Flavivirus, Pestivirus and Rubivirus--and additional members. The main characteristics of the family are as follows: single-stranded, linear RNA, molecular weight about 4 X 10(6). Virions have isometric nucleocapsids surrounded by a lipoprotein envelope containing host cell lipid
J S, Porterfield +10 more
openaire +2 more sources
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
Pathogens, 2019 The mosquito-borne chikungunya virus (CHIKV) has become a major global health problem. Upon infection, chikungunya fever (CHIKF) can result in long-term joint pain and arthritis, and despite intense research, no licensed vaccine for CHIKV is available ...
Rafael Kroon Campos +5 more
doaj +1 more source
Инфекция и иммунитет, 2014 . This review summarizes data about rubella virus and its teratogenic action, congenital rubella syndrome (CRS), modern methods of diagnostics and prevention of infection.
A. J. Antipova
doaj +1 more source
Mayaro Virus in Wild Mammals, French Guiana
Emerging Infectious Diseases, 2003 A serologic survey for Mayaro virus (Alphavirus, Togaviridae) in 28 wild nonflying forest mammal species in French Guiana showed a prevalence ranging from 0% to 52% and increasing with age.
Benoît de Thoisy +4 more
doaj +1 more source
Alphavirus-Induced Membrane Rearrangements during Replication, Assembly, and Budding
Pathogens, 2021 Alphaviruses are arthropod-borne viruses mainly transmitted by hematophagous insects that cause moderate to fatal disease in humans and other animals. Currently, there are no approved vaccines or antivirals to mitigate alphavirus infections.
Zeinab Elmasri +2 more
doaj +1 more source
Comparative analysis of the extent of protein-protein interactions in icosahedral viral capsids. [PDF]
Protein SciAbstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Zimmerman NJ, Labra OR, Reddy VS.
europepmc +2 more sources
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
, 2017 The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source