Results 111 to 120 of about 16,123 (208)

Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats

, 2013
[[abstract]]Andrographolide is the most abundant terpenoid of A. paniculata which is used in the treatment of diabetes. In this study, we investigated the effects of A.
Chen, HW;Chen, HW;黃晉修;Huang, Chin-Shiu;Liu, PF;Liu, PF;Li, CC;Li, CC;Chen, CT;Chen, CT;Liu, CT;Liu, CT;Chiang, JR;Chiang, JR;Yao, HT;Yao, HT;李宗貴;Lii, Chong-Kuei
core  

Sesamin exhibits potential food-drug interactions through the inhibition of cytochrome P450s and human UDP-glucuronosyltransferases <i>in vitro</i>. [PDF]

RSC Adv
Yin H, Zhu L, Wang X, Wang Z, Wang H, Liu Y.   +5 more
europepmc   +1 more source

Tumor-derived Parathyroid Hormone-Related Protein Is Associated with Suppression of Cytochrome P450 Expression: Evidence From Multimodal Transcriptomics. [PDF]

ACS Pharmacol Transl Sci
Fujita I, Kaji T, Noguchi I, Tokumaru K, Maeda H, Maruyama T, Watanabe H.   +6 more
europepmc   +1 more source

Screening of binding by antidiabetic drugs to normal vs AGE-modified human serum albumin through covalent immobilization and microscale affinity chromatography. [PDF]

J Chromatogr B Analyt Technol Biomed Life Sci
Woolfork AG, Rahman MM, Graham LM, Hage DS.   +3 more
europepmc   +1 more source

Dynamic Ca2+-Dependent Transcription Links Metabolic Stress to Impaired β-Cell Identity. [PDF]

Diabetes
Osipovich AB, Dickerson MT, Cartailler JP, Shrestha S, Wright NM, Jacobson DA, Magnuson MA.   +6 more
europepmc   +1 more source

Development of physiologically based liver distribution model that incorporates intracellular lipid partitioning and binding to fatty acid binding protein 1. [PDF]

J Pharmacol Exp Ther
Wen YW, Isoherranen N.
europepmc   +1 more source

Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms. [PDF]

J Neuroendocrinol
Lavoie O, Turmel A, Khouma A, Minbashi Moeini M, Liu C, Michael NJ, Caron A.   +6 more
europepmc   +1 more source

Effect of Tolbutamide on the Respiration of Heart Muscle Mitochondria

Tolbutamide, one of the hypoglycemic sulphonylurea drugs was found to decrease the respiratory control index of beef heart mitochondria as well as that of rat liver mitochondria.
KATSUMATA, KAZUO, HAGIHARA, MASAKO
core  

Biosensor cell array reveals temporal GABA secretion dynamics from pancreatic islets. [PDF]

Mol Metab
Stis AE, Lazimi CS, Ferreira SM, Cuaycal AE, Smurlick D, Hagan DW, Nakayama T, Gandhi SP, Smith E, Spicer TP, Phelps EA.   +10 more
europepmc   +1 more source

Type IIB PKA serves as the primary effector of Gs-coupled receptor-potentiated insulin secretion in mice by orchestrating ion channels and granule phenotype. [PDF]

Diabetologia
Liu Y, Ni Y, Xie C, Fan L, Jiang Y, Sun Q, Mao B, Huang C, Zhang Z, Yang Y, He M, Xiao L, Li Y, Liu R.   +13 more
europepmc   +1 more source