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Dynamics of the homotrimeric tolc transmembrane protein [PDF]

Efflux-mediated β-lactam resistance poses a significant challenge to public health,undermining the effectiveness of various β-lactam antibiotics against a multitude of clinicallyrelevant pathogenic bacteria. Structural and functional analyses have elucidated the role ofthe efflux protein TolC in several Gram-negative bacteria as a conduit for ...
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Outer Membrane Channel Protein TolC Regulates Escherichia coli K12 Sensitivity to Plantaricin BM-1 via the CpxR/CpxA Two-Component Regulatory System

Probiotics and Antimicrobial Proteins, 2020
Hongxing Zhang, Junhua Jin, Yuanhong Xie   +2 more
exaly  

Inhibitors of Antibiotic Efflux by AcrAB-TolC in Enterobacter aerogenes

Anti-Infective Agents, 2013
Lieutaud, Aurélie, Guinoiseau, E., Lorenzi, V., Guiliani, Mc, Lome, V., Brunel, Jm, Luciani, A., Casanova, J., Pages, Jm, Berti, Liliane, Bolla, J.M.   +10 more
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The TolC protein of Escherichia coli serves as a cell-surface receptor for the newly characterized TLS bacteriophage 1 1Edited by B. Holland

Journal of Molecular Biology, 2001
Greg J German, Rajeev Misra
exaly  

Multidrug resistance pump AcrAB-TolC is required for high-level, Tet(A)-mediated tetracycline resistance in Escherichia coli

Journal of Antimicrobial Chemotherapy, 2006
Paula A Vincent, Raúl A Salomon
exaly  

Structure of the Ligand-blocked Periplasmic Entrance of the Bacterial Multidrug Efflux Protein TolC

Journal of Molecular Biology, 2004
Matthew K Higgins, Jeyanthy Eswaran, Gebhard F X Schertler   +2 more
exaly  

A TolC-Like Protein of Actinobacillus pleuropneumoniae Is Involved in Antibiotic Resistance and Biofilm Formation

Frontiers in Microbiology, 2016
Sanjie Cao, Luhua Zhang, Gee W Lau
exaly  

Type I secretion and multidrug efflux: transport through the TolC channel-tunnel

Trends in Biochemical Sciences, 2001
Susan K Buchanan
exaly  

The TolC protein ofEscherichia coliK12 is synthesised in a precursor form

FEBS Letters, 1983
J Hackett, Rajeev Misra, Peter R Reeves   +2 more
exaly  

Interaction between the α-barrel tip of Vibrio vulnificus TolC homologs and AcrA implies the adapter bridging model

Journal of Microbiology, 2014
Saemee Song, Minho Lee, Nam-Chul Ha
exaly