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Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

open access: yesAdvanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang   +14 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of an essential oil obtained from the flowering aerial parts of <i>Thymus vulgaris</i> L. and/or <i>Thymus zygis</i> L. (thyme oil) for use in all animal species (FEFANA asbl). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +23 more
europepmc   +1 more source

Design and Analysis of Optical-Mechanical-Thermal Systems for a High-Resolution Space Camera. [PDF]

open access: yesSensors (Basel)
Liu X   +10 more
europepmc   +1 more source

Rapid Spur Gear Profile Inspection Using Chromatic Confocal Sensors. [PDF]

open access: yesSensors (Basel)
Chang BH   +4 more
europepmc   +1 more source
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Therapeutic induction of antigen-specific immune tolerance

Nature Reviews Immunology, 2023
The development of therapeutic approaches for the induction of robust, long-lasting and antigen-specific immune tolerance remains an important unmet clinical need for the management of autoimmunity, allergy, organ transplantation and gene therapy. Recent breakthroughs in our understanding of immune tolerance mechanisms have opened new research avenues ...
Jessica E. Kenison   +2 more
openaire   +4 more sources

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