Results 201 to 210 of about 4,498,564 (240)

Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis. [PDF]

J Clin Invest
Fondelli F, Willemyns J, Domenech-Garcia R, Mansilla MJ, Godoy-Tena G, Ferreté-Bonastre AG, Agúndez-Moreno A, Presas-Rodriguez S, Ramo-Tello C, Ballestar E, Martínez-Cáceres E.   +10 more
europepmc   +1 more source

The role of tryptophan metabolism and tolerogenic dendritic cells in maintaining immune tolerance: Insights into celiac disease pathogenesis. [PDF]

Immun Inflamm Dis
Asgari F, Khodadoust M, Nikzamir A, Jahani-Sherafat S, Rezaei Tavirani M, Rostami-Nejad M.   +5 more
europepmc   +1 more source

Ex Vivo-Generated Tolerogenic Dendritic Cells: Hope for a Definitive Therapy of Autoimmune Diseases. [PDF]

Curr Issues Mol Biol
Jonny, Sitepu EC, Nidom CA, Wirjopranoto S, Sudiana IK, Ansori ANM, Putranto TA.   +6 more
europepmc   +1 more source

Bridging the Gap Between Tolerogenic Dendritic Cells In Vitro and In Vivo: Analysis of Siglec Genes and Pathways Associated with Immune Modulation and Evasion. [PDF]

Genes (Basel)
Jansen DTSL, Nikolic T, den Hollander NHM, Zwaginga JJ, Roep BO.   +4 more
europepmc   +1 more source

CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells. [PDF]

PLoS Biol
Pellegrino B, David K, Rabani S, Lampert B, Tran T, Doherty E, Piecychna M, Meza-Romero R, Leng L, Hershkovitz D, Vandenbark AA, Bucala R, Becker-Herman S, Shachar I.   +13 more
europepmc   +1 more source

Design of TOLERANT: phase I/II safety assessment of intranodal administration of HSP70/mB29a self-peptide antigen-loaded autologous tolerogenic dendritic cells in patients with rheumatoid arthritis. [PDF]

BMJ Open
Stoppelenburg AJ, Schreibelt G, Koeneman B, Welsing P, Breman EJ, Lammers L, de Goede A, Duiveman-de Boer T, van Eden W, Leufkens P, de Vries IJM, Broere F, van Laar JM.   +12 more
europepmc   +1 more source

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Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases

Trends in Immunology, 2021
Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in vitro in response to various stimuli, including interleukin (IL)-10, transforming growth factor (TGF)-β, vitamin D3, corticosteroids, and rapamycin. In this review, we
Esteban Ballestar, Octavio Morante-Palacios, Federico Fondelli   +2 more
exaly   +3 more sources

Tolerogenic dendritic cells protect against acute kidney injury [PDF]

Kidney International, 2023
Ischemia reperfusion injury is a common precipitant of acute kidney injury that occurs following disrupted perfusion to the kidney. This includes blood loss and hemodynamic shock, as well as during retrieval for deceased donor kidney transplantation ...
Angus W. Thomson, Quan Nguyen, Ellis Patrick   +2 more
exaly   +2 more sources

Modulation of tolerogenic dendritic cells and autoimmunity

Seminars in Cell & Developmental Biology, 2015
A key function of dendritic cells (DCs) is to induce either immune tolerance or immune activation. Many new DC subsets are being recognized, and it is now clear that each DC subset has a specialized function. For example, different DC subsets may express different cell surface molecules and respond differently to activation by secretion of a unique ...
Sun Jung, Kim, Betty, Diamond
openaire   +2 more sources