Results 61 to 70 of about 396,801 (209)
Alveolar macrophages and Toll-like receptor 4 mediate ventilated lung ischemia reperfusion injury in mice. [PDF]
, 2012 BackgroundIschemia-reperfusion (I-R) injury is a sterile inflammatory process that is commonly associated with diverse clinical situations such as hemorrhage followed by resuscitation, transient embolic events, and organ transplantation.
Dodd-o, Jeffrey M +5 more
core +1 more source
Intracellular Toll-like Receptors [PDF]
Immunity, 2010 Foreign nucleic acids, the signature of invading viruses and certain bacteria, are sensed intracellularly. The nucleic acid-specific Toll-like receptors (TLRs) detect and signal within endolysosomal compartments, triggering the induction of cytokines essential for the innate immune response.
Blasius, Amanda L., Beutler, Bruce
openaire +2 more sources
Chicken Toll-like Receptor 3 Recognizes Its Cognate Ligand When Ectopically Expressed in Human Cells [PDF]
, 2007 Recognition of pathogens by toll-like receptors (TLRs) causes activation of signaling cascades that trigger cytokine secretion and, ultimately, innate immunity.
Bauer, Stefan +7 more
core +1 more source
Neonatal innate immunity and Toll-like receptor [PDF]
Korean Journal of Pediatrics, 2010 The innate immune response is the first line of defense against microbial infections. Innate immunity is made up of the surface barrier, cellular immunity and humoral immunity.
Hye Sun Yoon
doaj +1 more source
Toll-Like Receptor Evolution: Does Temperature Matter?
Frontiers in Immunology, 2022 Toll-like receptors (TLRs) recognize conserved pathogen-associated molecular patterns (PAMPs) and are an ancient and well-conserved group of pattern recognition receptors (PRRs).
Cármen Sousa +10 more
doaj +1 more source
Toll-Like Receptors and Leishmaniasis [PDF]
Infection and Immunity, 2008 More than 10 million people around the world are currently affected by Leishmania sp. (33). Infection with this protozoan parasite continues to be a problem in underdeveloped countries and is a continuous worry in developed countries due to the possibility of the disease afflicting tourists returning from countries where the organism is endemic (82 ...
Felipe F, Tuon +5 more
openaire +2 more sources
Molecular alterations of the TLR4-signaling cascade in canine epilepsy
BMC Veterinary Research, 2020 Background Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling acting as one key factor.
Eva-Lotta von Rüden +8 more
doaj +1 more source
Hypoallergenic fragment of Par j 2 increases functional expression of Toll-like receptors in atopic children [PDF]
, 2006 Parietaria judaica (Par j) is one of the main causes of allergy in the Mediterranean countries. The activation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) inhibits nasal inflammation of atopic ...
Bonsignore, G +7 more
core +1 more source
Cracking the Toll-like receptor code in fungal infections [PDF]
, 2010 Innate control of fungal infection requires the specific recognition of invariant fungal molecular structures by a variety of innate immune receptors, including Toll-like receptors.
Carvalho, Agostinho +2 more
core +1 more source
Tumor Biology, 2017 High mobility group box 1 and toll-like receptor 4/myeloid differentiation factor 88 signaling pathway have been indicated to have oncogenic effects in many cancers.
Yanqiu Yue +8 more
doaj +1 more source