Results 191 to 200 of about 537,344 (241)

Palmatine inhibits TRIF-dependent NF-kB pathway against inflammation induced by LPS in goat endometrial epithelial cells [PDF]

, 2017
Cheng, Z R, Dong, S, Na, L, Sang, M, Wang, D, Yan, B, Yan, Z, Yang, H, Yang, Z, Zhang, S   +9 more
core  

Mast cell-derived interleukin-4 mediates activation of dendritic cell during toll-like receptor 2-mediated inflammation. [PDF]

Front Immunol
Friedel J, Pierre S, Kolbinger A, Schäufele TJ, Aliraj B, Weigert A, Scholich K.   +6 more
europepmc   +1 more source

Insights into the Correlation between Toll-Like Receptor 2 Polymorphism and HBV-Related Disease Progression and Occurrence of Hepatocellular Carcinoma: A Case-Control Study in Egyptian Patients. [PDF]

Can J Infect Dis Med Microbiol
Elabd NS, Helal ML, Elkhayat M, Abd-ElKhalek HK, Ahmed DM, El-Shemy AM, Elsaadawy YS, Abdelmoneum RA, AboShabaan HS, Seddik RM.   +9 more
europepmc   +1 more source

Salmonella Typhi serine threonine kinase T4519 induces lysosomal membrane permeabilization by manipulating Toll-like receptor 2-Cystatin B-Cathepsin B-NF-κB-reactive oxygen species pathway and promotes survival within human macrophages. [PDF]

PLoS Pathog
Chakraborty S, Ganguli D, Nagaraja T, Gope A, Dey S, Pal A, Mandal RS, Das SS, Das S.   +8 more
europepmc   +1 more source

Expression of toll-like receptors in cartilage endplates cells: a role of toll-like receptor 2 in pro-inflammatory and -catabolic gene expression

Mengis T, Bernhard L, Herger N, Heggli I, Devan J, Marcus R, Laux C, Brunner F, Farshad M, Distler O, Dudli S.   +10 more
europepmc   +1 more source

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Toll-like receptor 2 signaling in liver pathophysiology.

Life Sciences, 2021
Chronic liver diseases (CLD) are among the major cause of mortality and morbidity worldwide. Despite current achievements in the area of hepatitis virus, chronic alcohol abuse and high-fat diet are still fueling an epidemic of severe liver disease, for ...
Anteneh Getachew, Muzammal Hussain, Xinping Huang, Yin-xiong Li   +3 more
semanticscholar   +3 more sources

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

Nature, 1998
Vertebrates and invertebrates initiate a series of defence mechanisms following infection by Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major component of the cell wall of the invading pathogen. In humans, monocytes and macrophages respond to LPS by inducing the expression of cytokines, cell-adhesion proteins, and ...
Ruey-Bing Yang, M. Mark, A. Gray, A. Huang, M. Xie, Min Zhang, A. Goddard, W. Wood, A. Gurney, P. Godowski   +9 more
semanticscholar   +3 more sources

Toll-like Receptor 2 and Toll-like Receptor 4 Expression in Human Adrenals

Hormone and Metabolic Research, 2004
Toll-like receptors (TLRs) are key elements in the innate immune response, functioning as pattern-recognition receptors for the detection and response to endotoxins and other microbial ligands. Inflammatory cytokines play an important role in the activation of the hypothalamic-pituitary-adrenal HPA axis during inflammation and sepsis.
Bornstein, SR, Schumann, RR, Rettori, V, McCann, SM, Zacharowski, KD   +4 more
openaire   +3 more sources

Simple synthetic toll-like receptor 2 ligands

Bioorganic & Medicinal Chemistry Letters, 2011
Stimulation of toll-like receptor 2 (TLR2) by bacterial lipoproteins induces fast non-specific immune responses against pathogens followed by slow but specific adaptive immune responses. Development of synthetic TLR2 agonists/antagonists would be useful in the prevention of different infectious and immunologic disorders.
Abdel-Aal, Abu-Baker M., Al-Isae, Kalifa, Zaman, Mehfuz, Toth, Istvan   +3 more
openaire   +3 more sources

Toll-like receptor 2 and Toll-like receptor 4 polymorphisms in invasive pneumococcal disease

Microbes and Infection, 2007
Toll-like receptors (TLRs) recognize distinct pathogen-associated molecular patterns and trigger anti-microbial host defense responses. Several in vitro and in vivo studies in mice indicate that TLR2 and TLR4 are involved in the defense against Streptococcus pneumoniae. Studies have revealed associations between polymorphisms in TLRs and human diseases.
Moens, L., Verhaegen, J., Pierik, M.J., Vermeire, S., de Boeck, K., Peetermans, W.E., Bossuyt, X.   +6 more
openaire   +3 more sources