Results 221 to 230 of about 460,890 (351)

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Dual-Action Theranostic Nanoparticles Delivering Toll-Like Receptor 2 Inhibitors and Chemotherapy Target Breast Cancer Cells and the Tumor Microenvironment. [PDF]

Int J Nanomedicine
Di Lorenzo A, Romiti C, Amaolo A, Cossu C, Iacoviello A, Curcio C, Forni M, Zanini C, Cavallo F, Ferrauto G, Di Gregorio E, Conti L.   +11 more
europepmc   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

<i><b>Muribaculum intestinale</b></i> <b>negatively impacts glioma growth in mice through the toll-like receptor 2</b>. [PDF]

Gut Microbes
Marrocco F, Cocozza G, Antonangeli F, Khan R, Pietropaolo G, Elkihel A, Favaretto G, Lin X, Mancinelli R, Busdraghi LM, Reccagni A, Scarno G, Sciumè G, Laffranchi M, Peng L, Iebba V, Sozzani S, D'Alessandro G, Limatola C.   +18 more
europepmc   +1 more source

Toll-like receptor induced inflammation causes local bone formation

It is well established that inflammatory processes in the vicinity of bone often induce osteoclast formation and bone resorption. Effects on bone formation by inflammatory processes are much less studied and available information is partly contradictory.
Lerner, Ulf,, Lindholm, Catharina, Movérare-Skrtic, Sofia, Henning, Petra, ALi, Kassem,, Souza, Pedro, Lundberg, Pernilla,   +6 more
core  

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Induced pluripotent stem cell-derived platelets kill multidrug-resistant <i>Staphylococcus aureus</i> via Toll-like receptor 2-MyD88 signaling and immunoglobulin G/FcγRIIA engagement. [PDF]

Res Pract Thromb Haemost
Lin Q, Nonomura K, Stirblyte I, Nakamura S, Uchiyama S, Yamaguchi M, Kawabata S, Nagao M, Suzuki-Inoue K, Nizet V, Eto K, Sugimoto N.   +11 more
europepmc   +1 more source

Chronic obstructive pulmonary disease and asthma‐associated Proteobacteria, but not commensal Prevotella spp., promote Toll‐like receptor 2‐independent lung inflammation and pathology

Immunology, 2015
J. M. Larsen, Hanieh Musavian, T. Butt, C. Ingvorsen, A. H. Thysen, S. Brix   +5 more
semanticscholar   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Toll like receptor 2 mediated exacerbation of sepsis associated acute kidney injury by renal congestion in mice. [PDF]

Sci Rep
Nakamura I, Umehara M, Yagi-Tomita A, Yamamoto S, Sawai S, Nakamura M, Minamida A, Yamauchi-Sawada H, Sunahara Y, Matoba Y, Okuno-Ozeki N, Nakai K, Nakata T, Kitani T, Yamashita N, Komaki K, Kirita Y, Tamagaki K, Matoba S, Kusaba T.   +19 more
europepmc   +1 more source