Results 301 to 310 of about 460,890 (351)

A scaffold vaccine to promote tumor antigen cross-presentation via sustained toll-like receptor-2 (TLR2) activation. [PDF]

Bioact Mater
Xie D, Han C, Chen C, Liao Z, Campos de Souza S, Niu Y, Mano JF, Dong L, Wang C.   +8 more
europepmc   +1 more source

Mast cell-derived interleukin-4 mediates activation of dendritic cell during toll-like receptor 2-mediated inflammation. [PDF]

Front Immunol
Friedel J, Pierre S, Kolbinger A, Schäufele TJ, Aliraj B, Weigert A, Scholich K.   +6 more
europepmc   +1 more source

Toll-like Receptors and Type 2 Diabetes

Journal of Diabetes & Metabolism, 2010
openaire   +1 more source

Expression of toll-like receptors in cartilage endplates cells: a role of toll-like receptor 2 in pro-inflammatory and -catabolic gene expression

Mengis T, Bernhard L, Herger N, Heggli I, Devan J, Marcus R, Laux C, Brunner F, Farshad M, Distler O, Dudli S.   +10 more
europepmc   +1 more source

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Toll-like Receptor 2 and Toll-like Receptor 4 Expression in Human Adrenals

Hormone and Metabolic Research, 2004
Toll-like receptors (TLRs) are key elements in the innate immune response, functioning as pattern-recognition receptors for the detection and response to endotoxins and other microbial ligands. Inflammatory cytokines play an important role in the activation of the hypothalamic-pituitary-adrenal HPA axis during inflammation and sepsis.
Bornstein, SR, Schumann, RR, Rettori, V, McCann, SM, Zacharowski, KD   +4 more
openaire   +3 more sources

The Toll of Toll-Like Receptors, Especially Toll-Like Receptor 2, on Murine Atherosclerosis

Current Drug Targets, 2007
At one time, atherosclerosis was thought to be a simple lipid storage disease. However, it is now recognized as a chronic and progressive inflammation of the arterial wall. Gene deletion experiments in murine models of atherosclerosis that reduce the inflammatory process also reduce disease severity.
L K, Curtiss, P S, Tobias
openaire   +2 more sources

Toll-like receptor 2 signaling in liver pathophysiology

Life Sciences, 2021
Chronic liver diseases (CLD) are among the major cause of mortality and morbidity worldwide. Despite current achievements in the area of hepatitis virus, chronic alcohol abuse and high-fat diet are still fueling an epidemic of severe liver disease, for which, an effective therapy has yet not been discovered. In particular, the therapeutic regimens that
Anteneh, Getachew, Muzammal, Hussain, Xinping, Huang, Yinxiong, Li   +3 more
openaire   +2 more sources

Expression of Toll-like Receptor 2 and Toll-like Receptor 4 in Tuberculous Pleural Effusion

Medicinal Chemistry, 2017
Toll-like receptor-2 (TLR2) and Toll-like receptor-4 (TLR4) have been reported to play a crucial role in tuberculosis, however, little is known about their expression in tuberculous pleuritis.The goal of this work is to explore the expressions of TLR2 and TLR4 in tuberculous pleuritis and their predominant expressions on cells.Levels of soluble TLR2 ...
Yingzhong, Lin, Tingmei, Feng, Jiao, Lan, Chunxia, Chen, Zhiqiang, Qin, Yanbin, Wu, Huanzhong, Shi, Jianbo, Ye, Caizhou, Wei, Wu, Wang, Luying, Huang   +10 more
openaire   +2 more sources

Toll-like receptor 2 and Toll-like receptor 4 polymorphisms in invasive pneumococcal disease

Microbes and Infection, 2007
Toll-like receptors (TLRs) recognize distinct pathogen-associated molecular patterns and trigger anti-microbial host defense responses. Several in vitro and in vivo studies in mice indicate that TLR2 and TLR4 are involved in the defense against Streptococcus pneumoniae. Studies have revealed associations between polymorphisms in TLRs and human diseases.
Moens, L., Verhaegen, J., Pierik, M.J., Vermeire, S., de Boeck, K., Peetermans, W.E., Bossuyt, X.   +6 more
openaire   +3 more sources

Salivary and Plasma Levels of Toll‐Like Receptor 2 and Toll‐Like Receptor 4 in Chronic Periodontitis

Journal of Periodontology, 2011
Background: This cross‐sectional study was planned to investigate whether patients with chronic periodontitis exhibit different salivary or plasma concentrations of Toll‐like receptor (TLR) 2 and TLR4 compared to subjects who are clinically healthy.Methods: Whole saliva and plasma samples were obtained and full‐mouth clinical periodontal measurements ...
Buduneli, Nurcan, Ozcaka, Ozgun, Nalbantsoy, Ayse   +2 more
openaire   +3 more sources