CD14 and Toll-like receptor 4 promote fibrillar Aβ42 uptake by microglia through clathrin-mediated pathway [PDF]
舞 藤倉
openalex
Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta‐ defensin‐ 2 via toll‐ like receptor 4 signalling [PDF]
Dong Kyung Sung +5 more
openalex +1 more source
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu +4 more
wiley +1 more source
Mapping the intracellular HMGB1 interactome and alterations induced by Toll-like receptor 4 activation. [PDF]
Heinbäck R +6 more
europepmc +1 more source
A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
RETRACTION: Qi-Dong-Huo-Xue-Yin Inhibits Inflammation in Acute Lung Injury in Mice via Toll-Like Receptor 4/Caveolin-1 Signaling. [PDF]
Alternative Medicine EC.
europepmc +1 more source
Effect of Puerarin on Chronic Alcoholic Encephalopathy by Modulating the “Microbiota‐Gut‐Brain Axis” Lipopolysaccharides/Toll‐Like Receptors 4/Nuclear Factor Kappa‐B Inflammatory Pathway [PDF]
Lei Zhang +5 more
openalex +1 more source
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng +8 more
wiley +1 more source
Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll-like receptor 4-dependent macrophage activation in asthma. [PDF]
Li G +9 more
europepmc +1 more source

