Modulation of Toll-like Receptors with Natural Compounds: A Therapeutic Avenue Against Inflammaging? [PDF]
Andrei C +3 more
europepmc +1 more source
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny +12 more
wiley +1 more source
Toll-like receptors and their role in the pathogenesis of myasthenia gravis: a comprehensive review. [PDF]
Zheng X +5 more
europepmc +1 more source
Postischemic reperfusion injury to allografts - A case for `innate immunity'? [PDF]
Land, Walter
core +1 more source
A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
Current update on toll-like receptors and prostate cancer: a decade of progress and emerging insights. [PDF]
Janjirala J +3 more
europepmc +1 more source
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng +8 more
wiley +1 more source
Toll-like receptors (TLRs) in the trained immunity era. [PDF]
Alexopoulou L, Irla M.
europepmc +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Erratum for Petronglo et al., "Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of <i>Staphylococcus aureus</i> Osteomyelitis". [PDF]
Petronglo JR +10 more
europepmc +1 more source

