Results 231 to 240 of about 300,180 (287)

Evidence against the role of toll-like receptors 7 and 8 in sex selection in mice, cattle, and humans. [PDF]

iScience
Zhao R, Liu J, Bakhtari A, Shen J, Fayad-Costa A, Wang B, Tian X.   +6 more
europepmc   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Role of Toll-Like Receptors in Myeloid Neoplasms: Focuses on the Molecular Mechanisms and Clinical Impact on Myelodysplastic Syndromes, Acute Myeloid Leukemia, and Chronic Myeloid Leukemia. [PDF]

APMIS
Cavalcante CBA, Chaves AC, de Oliveira VS, de Araújo MAS, Cunha E Silva TM, Goes JVC, de Oliveira RTG, Pinheiro RF, Ribeiro-Junior HL.   +8 more
europepmc   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Making teaching an attractive profession: What are the challenges and opportunities for minority ethnic teachers in England?

British Educational Research Journal, EarlyView.
Abstract This paper explores the challenges and opportunities surrounding the recruitment and retention of minority ethnic teachers in England. Drawing on interview data from 33 teachers and school leaders of diverse ethnic backgrounds, it investigates whether racialised barriers identified in earlier research have shifted in the current context of ...
Antonina Tereshchenko, Feyisa Demie, Stephen Gorard, Yiyang Gao, Beng Huat See, Nadia Siddiqui   +5 more
wiley   +1 more source

Unveiling the molecular interactions between bisphenol A and the cell surface Toll-like receptors: Implications for immune health. [PDF]

Toxicol Rep
Rajak P, Ganguly A.
europepmc   +1 more source

Mindfulness and resilience: The experiences of global majority students in a mindfulness intervention Programme at a UK university

British Educational Research Journal, EarlyView.
Abstract Wellbeing in higher education (HE) in the United Kingdom has been increasingly prioritised for many institutions, with a growing demand for student support requests. There are various determinants in life that can influence mental health. As such, protected characteristics, including race, can indicate that students who are Black or Asian ...
Amy Bywater, Helen Keane
wiley   +1 more source

Altered Expression of Toll-Like Receptors and Key Signaling Genes in Sertoli Cells of Azoospermic Patients. [PDF]

J Reprod Infertil
Lakpour MR, Aflatoonian R, Sadighi Gilani MA, Hajihosseini R, Sabbaghian M.   +4 more
europepmc   +1 more source

Inflammatory Modulation of Toll-like Receptors in Periodontal Ligament Stem Cells: Implications for Periodontal Therapy. [PDF]

Cells
Mekhemar M, Terheyden I, Dörfer C, Fawzy El-Sayed K.   +3 more
europepmc   +1 more source

Erratum: Asthma With Bronchial Hypersecretion: Expression of Mucins and Toll-Like Receptors in Sputum and Blood [Corrigendum]. [PDF]

J Asthma Allergy
europepmc   +1 more source