Results 241 to 250 of about 300,180 (287)
The relationship between toll-like receptors 9 gene rs5743836 polymorphism and lymphoma risk: a meta-analysis. [PDF]
BMC CancerYan M +7 more
europepmc +1 more source
Toll-Like Receptors Agonists: First-Line Defense Tools in the Pandemic Preparedness Arsenal? [PDF]
Arch Iran MedHabibzadeh F +3 more
europepmc +1 more source
Special Issue "The Role of Toll-Like Receptors (TLRs) in Infection and Inflammation 2.0". [PDF]
Int J Mol SciKircheis R, Planz O.
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Annual Review of Immunology, 2003
The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defense mechanisms. In drosophila antimicrobial responses rely on two signaling pathways: the Toll pathway and the IMD pathway.
Kiyoshi, Takeda +2 more
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The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defense mechanisms. In drosophila antimicrobial responses rely on two signaling pathways: the Toll pathway and the IMD pathway.
Kiyoshi, Takeda +2 more
openaire +3 more sources
Current Protocols in Immunology, 2007
AbstractThe mammalian Toll‐like receptor (TLR) family consists of 13 members, and recognizes specific patterns of microbial components, called pathogen‐associated molecular patterns (PAMPs). TLR‐dependent recognition of PAMPs leads to activation of the innate immune system, which subsequently leads to activation of antigen‐specific adaptive immunity ...
Kiyoshi, Takeda, Shizuo, Akira
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AbstractThe mammalian Toll‐like receptor (TLR) family consists of 13 members, and recognizes specific patterns of microbial components, called pathogen‐associated molecular patterns (PAMPs). TLR‐dependent recognition of PAMPs leads to activation of the innate immune system, which subsequently leads to activation of antigen‐specific adaptive immunity ...
Kiyoshi, Takeda, Shizuo, Akira
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Critical Care Medicine, 2002
The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of sepsis and septic shock, however, an exaggerated systemic response may, in fact, contribute to the morbidity and mortality associated with overwhelming infections.
Egil, Lien, Robin R, Ingalls
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The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of sepsis and septic shock, however, an exaggerated systemic response may, in fact, contribute to the morbidity and mortality associated with overwhelming infections.
Egil, Lien, Robin R, Ingalls
openaire +3 more sources
Microbes and Infection, 2000
Toll-like receptors (TLRs) are a growing family of molecules involved in innate immunity. Accumulating evidence suggests that TLR molecules are involved in signalling receptor complexes which recognise components of Gram-positive and Gram-negative bacteria and mycobacteria.
M, Muzio, A, Mantovani
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Toll-like receptors (TLRs) are a growing family of molecules involved in innate immunity. Accumulating evidence suggests that TLR molecules are involved in signalling receptor complexes which recognise components of Gram-positive and Gram-negative bacteria and mycobacteria.
M, Muzio, A, Mantovani
openaire +2 more sources
Nature Reviews Immunology, 2004
One of the mechanisms by which the innate immune system senses the invasion of pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize specific molecular patterns that are present in microbial components. Stimulation of different TLRs induces distinct patterns of gene expression, which not only leads to the activation of ...
Shizuo, Akira, Kiyoshi, Takeda
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One of the mechanisms by which the innate immune system senses the invasion of pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize specific molecular patterns that are present in microbial components. Stimulation of different TLRs induces distinct patterns of gene expression, which not only leads to the activation of ...
Shizuo, Akira, Kiyoshi, Takeda
openaire +2 more sources
Cell and Tissue Research, 2010
Analysis of the genomes of two distantly related bird species, chicken and zebra finch (divergence of about 100 million years), indicate that there are ten avian toll-like receptors and that five of these, TLR2a, 2b, 3, 4, 5 and 7, are clear orthologs to TLRs found in mammals.
Robert, Brownlie, Brenda, Allan
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Analysis of the genomes of two distantly related bird species, chicken and zebra finch (divergence of about 100 million years), indicate that there are ten avian toll-like receptors and that five of these, TLR2a, 2b, 3, 4, 5 and 7, are clear orthologs to TLRs found in mammals.
Robert, Brownlie, Brenda, Allan
openaire +2 more sources