Results 81 to 90 of about 180,223 (258)
The role of innate immune signals in immunity to Brucella abortus
Frontiers in Cellular and Infection Microbiology, 2012 Innate immunity serves as the first line of defense against infectious agents such as intracellular bacteria. The innate immune platform includes Toll-like receptors, retinoid acid-inducible gene-I-like receptors and other cytosolic nucleic acid sensors,
Marco Tulio R. Gomes +7 more
doaj +1 more source
Glycogen synthase kinase-3β mediates toll-like receptors 4/nuclear factor kappa-B-activated cerebral ischemia-reperfusion injury through regulation of fat mass and obesity-associated protein. [PDF]
Brain Circ, 2023 Xu K +5 more
europepmc +1 more source
The role of toll-like receptor 4 in tumor microenvironment
Oncotarget, 2017 Tumors are closely related to chronic inflammation, during which there are various changes in inflammatory sites, such as immune cells infiltration, pro-inflammation cytokines production, and interaction between immune cells and tissue cells. Besides, substances, released from both tissue cells attacked by exogenous etiologies, also act on local cells.
Li, Jing +3 more
openaire +3 more sources
Advanced Science, EarlyView.Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms
Journal of Immunology Research, 2019 The bioactive and anti-inflammatory role of human milk components has been recognized; active milk components include soluble forms of Toll-like receptors (TLRs).
Chiara Cattaneo +10 more
doaj +1 more source
TH Open, 2019 Background Like immune cells, platelets express the repertoire of toll-like receptors (TLR), among them TLR2 and TLR4, which are important for the recognition of bacterial patterns. Receptor-mediated functional effects in platelets have been investigated,
Juergen Koessler +6 more
doaj +1 more source
Association of Toll-like receptors 4 (TLR-4) gene expression and polymorphisms in patients with severe asthma. [PDF]
J Med Life, 2021 Shukur W +8 more
europepmc +1 more source
Advanced Science, EarlyView.Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha +4 more
wiley +1 more source
Expression of Toll-like receptors 2 and 4 in gingivitis and chronic periodontitis.
Indian Journal of Dental Research, 2006 Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection by oral bacteria.
Sarah S +3 more
doaj
Deficiency of Toll-like receptors 2, 3 or 4 extends life expectancy in Huntington’s disease mice
Heliyon, 2018 Huntington’s disease (HD), an autosomal dominant neurodegenerative disorder characterized by progressive striatal and cortical atrophy, has been strongly linked with neuroinflammation. Toll-like receptors, a family of innate immune receptors, are a major
Kathleen Griffioen +2 more
doaj +1 more source