Results 101 to 110 of about 196,208 (305)
Differential expression of Toll-like receptors and inflammatory cytokines in ovine interdigital dermatitis and footrot [PDF]
, 2014 Footrot is a common inflammatory bacterial disease affecting the health and welfare of sheep worldwide. The pathogenesis of footrot is complex and multifactorial.
Jasmeet Kaler +20 more
core +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Advanced Science, EarlyView.Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source
Toll-Like Receptors in Secondary Obstructive Cholangiopathy
Gastroenterology Research and Practice, 2011 Secondary obstructive cholangiopathy is characterized by intra- or extrahepatic bile tract obstruction. Liver inflammation and structural alterations develop due to progressive bile stagnation.
A. G. Miranda-Díaz +5 more
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Allergic rhinitis and genetic components: focus on Toll-like receptors (TLRs) gene polymorphism [PDF]
, 2010 Zhiwei Gao1, Donna C Rennie2, Ambikaipakan Senthilselvan11Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada; 2College of Nursing and Canadian Centre for Health and Agricultural Safety ...
Ambikaipakan Senthilselvan +2 more
core
Toll-like receptors and inflammatory bowel disease [PDF]
The fundamental purpose of the innate immune system is to protect a host against pathogens. In this context, the innate immune system in the gastrointestinal tract is unique because of the numerous foreign organisms such as bacteria living within it ...
Fukata, Masayuki, Abreu, Maria T
core +1 more source
Advanced Science, EarlyView.L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen +17 more
wiley +1 more source
A study of the modulation of Toll-like receptor signalling in macrophages by Annexin-1 [PDF]
, 2010 PhDAnnexin-A1 (AnxA1) is an endogenous anti-inflammatory protein that has been shown to exert a protective role against the lethal effects induced by the Toll-like receptor (TLR) 4 agonist lipopolysaccharide (LPS).
Polycarpou, Anastasia
core
Frontiers in ImmunologyAs a chronic inflammatory illness of the respiratory system, asthma occurs due to various factors and is characterized by a T helper 2 (Th2)-skewed immune response, airway hyperresponsiveness, and reversible airflow obstruction. Toll-like receptors (TLRs)
Xinyi Xu +5 more
doaj +1 more source
Toll-Like Receptors: Role in Dermatological Disease
Mediators of Inflammation, 2010 Toll-like receptors (TLRs) are a class of conserved receptors that recognize pathogen-associated molecular patterns (PAMPs) present in microbes. In humans, at least ten TLRs have been identified, and their recognition targets range from bacterial ...
Aswin Hari +3 more
doaj +1 more source