Results 161 to 170 of about 179,059 (207)
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Chain-extension and thermal behaviors of poly(p-dioxanone) with toluene-2,4-diisocyanate

Reactive and Functional Polymers, 2005
Abstract A method for enhancing the molecular weight of poly( p -dioxanone) (PPDO) has been provided in this investigation. Higher molecular weight biodegradable polymers have been prepared by chain-extending method from lower molecular weight PPDO using toluene-2,4-diisocyanate (TDI) as a chain extender.
Qiao Lai   +4 more
openaire   +1 more source

Catalytic Effects of Water Clusters on the Hydrolysis of Toluene-2,4-diisocyanate: A DFT Study

Bulletin of the Chemical Society of Japan, 2015
Abstract The reaction mechanism between 2,4-diisocyanatotoluene (2,4-TDI) and water clusters was carried out using density functional theory (DFT) at the B3LYP/6-311++G(d,p) level. The reaction can occur via two pathways. In path a, the 2,4-TDI reacts with water molecules by the attack across the N=C bond to form carbamic acid further ...
Yuan Yuan   +6 more
openaire   +1 more source

Route-Dependent Comparative Metabolism of [14C]Toluene 2,4-Diisocyanate and [14C]Toluene 2,4-Diamine in Fischer 344 Rats

Toxicology and Applied Pharmacology, 1994
This study was initiated to evaluate the pharmacokinetics/metabolism of 14C-labeled toluene 2,4-diisocyanate (2,4-[14C]-TDI) following oral and inhalation exposure in the rat. For comparison, the pharmacokinetics/metabolism of toluene 2,4-diamine (2,4-[14C]TDA) was also evaluated. Groups of 3 or 4 male rats were given either a single 60 mg/kg oral dose
C, Timchalk, F A, Smith, M J, Bartels
openaire   +2 more sources

Delayed-Type Asthmatic Response Induced by Repeated Intratracheal Exposure to Toluene-2,4-Diisocyanate in Guinea Pigs

International Archives of Allergy and Immunology, 2005
<i>Background:</i> A toluene-2,4-diisocyanate (TDI)-induced asthma model, in which delayed-type hypersensitivity-like asthmatic airway obstruction is elicited restrictively in the lung, has never been developed. <i>Methods:</i> Guinea pigs were percutaneously sensitized with TDI.
Takeshi, Nabe   +6 more
openaire   +2 more sources

Efficacy of Repeated Pretreatment with Olopatadine Hydrochloride on Rhinitis Induced by Intranasal Instillation of Toluene-2,4-Diisocyanate in Rats

Pharmacology, 2009
It is well known that starting treatment for cedar pollinosis therapy with second-generation antihistamines before the initial day of pollen scattering can relieve nasal symptom severity during the pollen season. Olopatadine hydrochloride (olopatadine) is an antiallergic agent with histamine H<sub>1</sub> receptor antagonistic action.
Tadafumi, Tamura, Naoya, Kimoto
openaire   +2 more sources

Toluene 2,4-Diisocyanate

2000
Abstract Toluene 2,4-diisocyanate (TDI) is widely used in the pro duction of polyurethane foams for insulation and in the synthesis of plastics. Common commercial grades of TDI are a mixture of 80% of the 2,4-isomer and 20% of the 2,6-isomer. The 2,4-isomer is more volatile and constitutes the overwhelming component of most industrial
openaire   +1 more source

New combined phenol/hindered amine photo- and thermal-stabilizers based on toluene-2,4-diisocyanate

Polymer Degradation and Stability, 2003
Abstract Reactions of toluene-2,4-diisocyanate with different phenols and different HAS (hindered amine stabilizers) were used to prepare new combined phenol/HAS. As a phenol 2- tert -butyl-4-methoxyphenol ( I ); 2- tert -butyl-4-methylphenol ( II ); 2,4-di- tert -butyl-6-methylphenol ( III ) and 2,4-di- tert -butylphenol ( IV ) were used.
J. Mosnáček   +4 more
openaire   +1 more source

Modeling formation and distribution of toluene-2,4-diamine (TDA) after spillage of toluene-2,4-diisocyanate (TDI) into a river

Journal of Hazardous Materials, 2013
Toluene diisocyanate (TDI) is a large volume chemical used for the production of polyurethanes. It is sparingly soluble in water, but hydrolyses instantaneously liberating toluene diamine (TDA), which is highly reactive to TDI. The ecotoxicity of TDI is dominated by TDA.
openaire   +2 more sources

Asp–Tyr–Leu–Lys tetrapeptide inhibits airway inflammation in toluene‐2,4‐diisocyanate‐induced asthma mice

Clinical & Experimental Allergy, 2008
SummaryBackground Airway inflammation and remodelling contribute to chronic airway obstruction of asthma. Currently, no medication effectively controls airway remodelling and related vascular changes. Therefore, new strategies need to be developed.
M-H, Ahn   +7 more
openaire   +2 more sources

A method using toluene-2,4-diisocyanate and glutaraldehyde to stabilize and conjugate antigens to erythrocytes for use in passive hemagglutination tests

Journal of Immunological Methods, 1978
Erythrocytes were stabilized and activated for conjugation by simultaneous treatment with toluene-2,4-diisocyanate and glutaraldehyde. Following conjugation with an antigen, these cells were suitable for use in passive hemagglutination tests and could be stored in either hypo- or hyper-tonic solutions at 4 degrees C for at least 3 months without ...
D E, Mahan, R L, Copeland
openaire   +2 more sources

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