Results 171 to 180 of about 3,344 (226)

Polyurethane foam demonstrations: The unappreciated toxicity of toluene-2,4-diisocyanate

Journal of Chemical Education, 1974
The author describes an accident and the relevant safety precautions resulting from a spill of toluene-2,4-diisocyanate .
G. W. Rayner. Canham, M. B. Hocking
openaire   +1 more source

Blocked isocyanate. Reaction and thermal behaviour of the toluene 2,4‐diisocyanate dimer

Die Angewandte Makromolekulare Chemie, 1996
AbstractDue to the difference in reactivity between free isocyanates and uretdione rings, diisocyanate dimers can be used as blocked isocyanates. They offer the potential advantage that no volatile by‐products are formed. The toluene 2,4‐diisocyanate dimer contains one uretdione ring, formed by dimerization of two isocyanate groups, and two free ...
E. Querat, L. Tighzert, J. P. Pascault, K. Dušek   +3 more
openaire   +1 more source

Route-Dependent Comparative Metabolism of [14C]Toluene 2,4-Diisocyanate and [14C]Toluene 2,4-Diamine in Fischer 344 Rats

Toxicology and Applied Pharmacology, 1994
This study was initiated to evaluate the pharmacokinetics/metabolism of 14C-labeled toluene 2,4-diisocyanate (2,4-[14C]-TDI) following oral and inhalation exposure in the rat. For comparison, the pharmacokinetics/metabolism of toluene 2,4-diamine (2,4-[14C]TDA) was also evaluated. Groups of 3 or 4 male rats were given either a single 60 mg/kg oral dose
C, Timchalk, F A, Smith, M J, Bartels
openaire   +2 more sources

Study on the synthesis of toluene-2,4-diisocyanate via amine and carbonyl fluoride

Journal of Fluorine Chemistry, 2015
Abstract We presented recently a synthesis of toluene-2,4-diisocyanate (TDI) as one of the nine examples to verify the feasibility of an industrial appealing two-step method for isocyanates synthesis via amines and carbonyl fluoride (COF2). Because more investigation was considered to be necessary for future industrial application, the two-step ...
Ni Zhang, Xiaomeng Zhou, Hengdao Quan, Akira Sekiya   +3 more
openaire   +1 more source

Chain-extension and thermal behaviors of poly(p-dioxanone) with toluene-2,4-diisocyanate

Reactive and Functional Polymers, 2005
Abstract A method for enhancing the molecular weight of poly( p -dioxanone) (PPDO) has been provided in this investigation. Higher molecular weight biodegradable polymers have been prepared by chain-extending method from lower molecular weight PPDO using toluene-2,4-diisocyanate (TDI) as a chain extender.
Qiao Lai, Yu-Zhong Wang, Ke-Ke Yang, Xiu-Li Wang, Qiang Zeng   +4 more
openaire   +1 more source

Asp–Tyr–Leu–Lys tetrapeptide inhibits airway inflammation in toluene‐2,4‐diisocyanate‐induced asthma mice

Clinical & Experimental Allergy, 2008
SummaryBackground Airway inflammation and remodelling contribute to chronic airway obstruction of asthma. Currently, no medication effectively controls airway remodelling and related vascular changes. Therefore, new strategies need to be developed.
M-H, Ahn, B-J, Park, J-H, Kwon, S-H, An, J-W, Park, A S, Jang, T, Rhim, C-S, Park   +7 more
openaire   +2 more sources

New combined phenol/hindered amine photo- and thermal-stabilizers based on toluene-2,4-diisocyanate

Polymer Degradation and Stability, 2003
Abstract Reactions of toluene-2,4-diisocyanate with different phenols and different HAS (hindered amine stabilizers) were used to prepare new combined phenol/HAS. As a phenol 2- tert -butyl-4-methoxyphenol ( I ); 2- tert -butyl-4-methylphenol ( II ); 2,4-di- tert -butyl-6-methylphenol ( III ) and 2,4-di- tert -butylphenol ( IV ) were used.
J. Mosnáček, Š. Chmela, G. Theumer, W.D. Habicher, P. Hrdlovič   +4 more
openaire   +1 more source

Delayed-Type Asthmatic Response Induced by Repeated Intratracheal Exposure to Toluene-2,4-Diisocyanate in Guinea Pigs

International Archives of Allergy and Immunology, 2005
<i>Background:</i> A toluene-2,4-diisocyanate (TDI)-induced asthma model, in which delayed-type hypersensitivity-like asthmatic airway obstruction is elicited restrictively in the lung, has never been developed. <i>Methods:</i> Guinea pigs were percutaneously sensitized with TDI.
Takeshi, Nabe, Kanami, Yamauchi, Yasuhiro, Shinjo, Tomohiro, Niwa, Kenji, Imoto, Akihide, Koda, Shigekatsu, Kohno   +6 more
openaire   +2 more sources

Immobilization of antibody to a plastic surface by toluene 2,4-diisocyanate and its application to radioimmunoassay

Clinica Chimica Acta, 1983
A novel procedure to fix antibody on a plastic surface was developed, using a polystyrene tube treated with 0.5% toluene 2,4-diisocyanate (TC) dissolved in carbon tetrachloride. Using 125I-labelled IgG, we found that the rate of immobilization of IgG was significantly higher than that obtained by simple adsorption or coupling by glutaraldehyde in the ...
T, Saito, F, Nagai
openaire   +2 more sources

Catalytic Effects of Water Clusters on the Hydrolysis of Toluene-2,4-diisocyanate: A DFT Study

Bulletin of the Chemical Society of Japan, 2015
Abstract The reaction mechanism between 2,4-diisocyanatotoluene (2,4-TDI) and water clusters was carried out using density functional theory (DFT) at the B3LYP/6-311++G(d,p) level. The reaction can occur via two pathways. In path a, the 2,4-TDI reacts with water molecules by the attack across the N=C bond to form carbamic acid further ...
Yuan Yuan, Jiping Cao, Yali Liu, Aijuan Shi, Qing Zhang, Xiaoxiong Lin, Mingliang Wang   +6 more
openaire   +1 more source