Results 241 to 250 of about 103,968 (278)

Tonic Inhibition

Science, 2010
The neurotransmitter GABA is tonically released from cells through an anion channel with an unusually large pore.
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Inhibition of the tonic contraction in the treatment of erectile dysfunction

Expert Opinion on Therapeutic Targets, 2003
Erectile dysfunction (ED) reduces the quality of life. It is estimated that 52% of men have some degree of ED, which is associated with ageing. While it is clear that there are a variety of current treatment options for ED, each of these has drawbacks and contraindications.
Liming, Jin, A Elizabeth, Linder, Thomas M, Mills, R Clinton, Webb   +3 more
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Brain stem tonic inhibition of thermoregulation in the rat

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1984
It was shown, by selective levels of decerebration, that a drop in body temperature occurred in a midpontine rat due to impairment in thermoregulatory responses. Lowering the level of decerebration to the lower pons restored a coordinated thermoregulatory response.
L, Amini-Sereshki, M R, Zarrindast
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Tonic descending inhibition in the stingray's spinal cord

Brain Research, 1985
Reflexes elicited by peripheral nerve stimulation were compared in decerebrated stingrays with the spinal cord intact, after a lesion of the dorsal spinal cord and after spinal transection. Reflexes elicited in decerebrated stingrays are tonically inhibited. Lesions of the dorsal spinal cord release this tonic descending inhibition.
Livingston, C.A., Leonard, R.B.
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Tonic cholinergic inhibition of spinal mechanical transmission

Pain, 1991
The present study examined the role of spinal cholinergic modulation of spinal mechanical and thermal transmission. Intrathecal administration of the cholinergic muscarinic receptor antagonists atropine or scopolamine in awake rats produced a dose-dependent decrease in the nociceptive mechanical withdrawal threshold of the rat tail.
M, Zhuo, G F, Gebhart
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Tonically Balancing Intracortical Excitation and Inhibition by GABAergic Gliotransmission

Neural Computation, 2014
For sensory cortices to respond reliably to feature stimuli, the balancing of neuronal excitation and inhibition is crucial. A typical example might be the balancing of phasic excitation within cell assemblies and phasic inhibition between cell assemblies. The former controls the gain of and the latter the tuning of neuronal responses.
Mei Hong Zheng, Takami Matsuo, Ai Miyamoto, Osamu Hoshino   +3 more
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Tonic in vivo inhibition of rabbit myometrial adrenergic receptors

Nature, 1981
With the development of radioligand binding assays for identifying hormone receptors directly, it has become evident that the number of receptors in a particular cell or tissue does not remain constant but can in fact, be regulated by a variety of agents1.
L E, Cornett, A, Goldfien, J M, Roberts
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Barium inhibition of the tonic component of frog atrial contraction

Pfl�gers Archiv European Journal of Physiology, 1985
Barium ions are able to substitute for calcium as charge carriers for the slow inward current of cardiac membrane. The effects of such a substitution on the mechanical activity of voltage-clamped frog atrial trabeculae have been investigated using the double mannitol gap device coupled with a mechano-electric transducer. In the presence of barium, the '
D, Potreau, G, Raymond
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Tonic opioid inhibition of the subiculo‐accumbens pathway

Synapse, 2001
AbstractThere is evidence to suggest that medium spiny neurons (MSNs) in the nucleus accumbens (NAS) should be sensitive to opiate compounds. However, neuronal responses in the NAS evoked by fimbria stimulation (F‐D) are insensitive to systemically or iontophoretically administered morphine.
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Substrate-Selective Inhibition of Mitochondrial Oxidations by Enhanced Tonicity

Nature, 1958
DURING an investigation of factors controlling rates of oxidation by mitochondria, it was found that variations of sucrose concentration in the suspending medium profoundly inhibited the oxygen consumption with some substrates but had much less effect with others.
D, JOHNSON, H, LARDY
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