Results 41 to 50 of about 1,008,908 (306)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Path Planning Method for Wire-Based Additive Manufacturing Processes

open access: yesModelling
The relevance of creating specialized computer programs that convert a virtual 3D model of an object into machine code (G-code) for controlling the process of 3D printing products from wire raw materials is substantiated.
Alexey Shcherbakov   +5 more
doaj   +1 more source

Comparative study on path interval determinations in filleted end milling

open access: yesEngineering and Applied Science Research, 2022
This study provides several findings obtained from the comparisons of path interval determinations in filleted end milling with a tool inclination. CNC milling machine is one of the core technologies in practical manufacturing.
Tsutomu Sekine, Kyoko Kameya
doaj  

Variable fused deposition modelling - concept design and tool path generation [PDF]

open access: yes, 2011
Current Fused Deposition Modelling (FDM) techniques use fixed diameter nozzles to deposit a filament of plastic layer by layer. The consequence is that the same small nozzle, essential for fine details, is also used to fill in relatively large volumes ...
Brooks, Hadley Laurence
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Process design and tool path generation for end milling considering tool life

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing
In mass production, the tool life of cutting tools is generally controlled by the number of parts to be machined and the machining time, making it difficult to operate each tool to its full life.
Rei MATSUMURA   +2 more
doaj   +1 more source

Research and Application of CNC Machining Method Based on CAD/CAM/Robot Integration

open access: yesAdvances in Multimedia, 2022
In order to improve the effect of intelligent CNC machining, this paper combines the CAD/CAM/Robot integration method to improve the CNC machining method and analyzes the tool path planning method and the path generation algorithm of the five-axis CNC ...
Xiangsong Yan
doaj   +1 more source

Investigation of Cutting Path Effect on Spindle Vibration and AE Signal Features for Tool Wear Monitoring in Micro Milling

open access: yesApplied Sciences, 2023
In the development of a tool wear monitoring system in milling, the complex cutting path always brings challenges to the system’s reliability in the production line.
Ci-Rong Huang, Ming-Chyuan Lu
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Tool-Path Problem in Direct Energy Deposition Metal-Additive Manufacturing: Sequence Strategy Generation

open access: yesIEEE Access, 2020
The tool-path problem has been extensively studied in manufacturing technologies, as it has a considerable impact on production time. Additive manufacturing is one of these technologies; it takes time to fabricate parts, so the selection of optimal tool ...
Maialen Murua   +3 more
doaj   +1 more source

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