Results 31 to 40 of about 381,354 (308)

Insights into the Structure and Function of TRIP-1, a Newly Identified Member in Calcified Tissues

open access: yesBiomolecules, 2023
Eukaryotic initiation factor subunit I (EIF3i), also called as p36 or TRIP-1, is a component of the translation initiation complex and acts as a modulator of TGF-β signaling. We demonstrated earlier that this intracellular protein is not only exported to
Jaison Arivalagan   +4 more
doaj   +1 more source

Identification of cross-talk pathways and PANoptosis-related genes in periodontitis and Alzheimer’s disease by bioinformatics analysis and machine learning

open access: yesFrontiers in Aging Neuroscience
Background and objectivesPeriodontitis (PD), a chronic inflammatory disease, is a serious threat to oral health and is one of the risk factors for Alzheimer’s disease (AD).
Xiantao Chen   +15 more
doaj   +1 more source

Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases

open access: yesFrontiers in Oncology, 2023
Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc.
Shaotai Wang   +8 more
doaj   +1 more source

Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation

open access: yesJournal of Nanobiotechnology
Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and programmed
Jiaxin Luo   +8 more
doaj   +1 more source

Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy–lysosome pathway in HNSCC

open access: yesInternational Journal of Oral Science, 2020
Epithelial–mesenchymal transition (EMT) is involved in both physiological and pathological processes. EMT plays an essential role in the invasion, migration and metastasis of tumours.
Xinchen Liu   +8 more
doaj   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

open access: yesAdvanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee   +4 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Molecular genetics of tooth development [PDF]

open access: yesCurrent Opinion in Genetics & Development, 2009
Organogenesis depends upon a well-ordered series of inductive events involving coordination of molecular pathways that regulate the generation and patterning of specific cell types. Key questions in organogenesis involve the identification of the molecular mechanisms by which proteins interact to organize distinct pattern formation and cell fate ...
openaire   +2 more sources

Bayesian semiparametric inference for multivariate doubly-interval-censored data [PDF]

open access: yes, 2010
Based on a data set obtained in a dental longitudinal study, conducted in Flanders (Belgium), the joint time to caries distribution of permanent first molars was modeled as a function of covariates.
De Iorio, Maria   +3 more
core   +4 more sources

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi   +7 more
wiley   +1 more source

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