Results 61 to 70 of about 15,088,934 (259)

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

Advanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun, Yan Wang, Fangying Shi, Wenhe Xie, Yiding Zhang, Heyuhan Zhang, Chunhui Deng, Limin Wu, Meihua Chen, Yonghui Deng   +9 more
wiley   +1 more source

Lactate inhibits mouse embryonic palatal mesenchyme cells chondrogenesis through AKT-PKM2 axis

BMC Oral Health
Background The development of the palate is a complex and continuous process, occurring in a series of stages with cartilage of being particular significance.
Mingyue Meng, Xige Zhao, Xiaoyu Zheng, Xiaotong Wang, Xia Peng, Zhiwei Wang, Shiteng Wang, Cui Guo, Juan Du   +8 more
doaj   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Interpretation of the WHO 2022 classification of head and neck tumours (5th Edition): The epithelial tumours of oral cavity and mobile tongue

Kouqiang hemian waike zazhi
The 5th edition of the Classification of Head and Neck Tumours by the World Health Organization (WHO) was published in March 2022. In the section on oral cavity and mobile tongue tumours, the classification of epithelial tumours in the 5th edition has ...
LI Jinwei, SHA Tong, ZHENG Kaijuan, NIE Mengdong, GUAN Weihang, SHI Ce   +5 more
doaj   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration

Journal of Translational Medicine, 2021
Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment approaches is still a challenge.
Hongbing Lin, Huishan Chen, Xuetao Zhao, Zhen Chen, Peipei Zhang, Yue Tian, Yawei Wang, Tong Ding, Lijing Wang, Yuqin Shen   +9 more
doaj   +1 more source

Grouping of tooth surfaces by susceptibility to caries: a study in 5-16 year-old children [PDF]

, 2004
Background The decline in caries has slowed and this may be indicative of variation in the susceptibility of differing teeth to caries. This study tests the hypothesis that in children, there are groups of tooth sites that exhibit differences in caries ...
Sheiham, A, Batchelor Paul A, Sheiham Aubrey, Aubrey Sheiham, Batchelor, P, Paul A Batchelor   +5 more
core   +2 more sources

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells

Kouqiang hemian waike zazhi
The role of bone marrow mesenchymal stem cells (BMSCs) in bone defect repair and bone regeneration has been extensively studied. Much evidence suggests that effective endogenous bone regeneration requires coordination of the immune system.
SHI Yan, GUO Hao, ZHENG Kaijuan, YANG Zhenming, QIANG Jinbiao, SHI Ce   +5 more
doaj   +1 more source

IDB Newsletter: Vol. 7, no. 4, October 1969

, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source