Results 61 to 70 of about 152,666 (314)

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring

International Journal of Oral Science
Periodontal disease is a risk factor for many systemic diseases such as Alzheimer’s disease and adverse pregnancy outcomes. Cleft palate (CP), the most common congenital craniofacial defect, has a multifaceted etiology influenced by complex genetic and ...
Xige Zhao, Xiaoyu Zheng, Yijia Wang, Jing Chen, Xiaotong Wang, Xia Peng, Dong Yuan, Ying Liu, Zhiwei Wang, Juan Du   +9 more
doaj   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration

Journal of Translational Medicine, 2021
Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment approaches is still a challenge.
Hongbing Lin, Huishan Chen, Xuetao Zhao, Zhen Chen, Peipei Zhang, Yue Tian, Yawei Wang, Tong Ding, Lijing Wang, Yuqin Shen   +9 more
doaj   +1 more source

Estimation of dental age in children in a Turkish population with tooth agenesis

, 2023
Aim: The aim of this study was to investigate tooth development according to chronological age in children with tooth agenesis and to determine whether the severity of tooth agenesis (hypodontia and oligodontia) has an effect on tooth development ...
Zuhal Kirzioglu, Canan Bayraktar Nahir
core   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Lactate inhibits mouse embryonic palatal mesenchyme cells chondrogenesis through AKT-PKM2 axis

BMC Oral Health
Background The development of the palate is a complex and continuous process, occurring in a series of stages with cartilage of being particular significance.
Mingyue Meng, Xige Zhao, Xiaoyu Zheng, Xiaotong Wang, Xia Peng, Zhiwei Wang, Shiteng Wang, Cui Guo, Juan Du   +8 more
doaj   +1 more source

Interpretation of the WHO 2022 classification of head and neck tumours (5th Edition): The epithelial tumours of oral cavity and mobile tongue

Kouqiang hemian waike zazhi
The 5th edition of the Classification of Head and Neck Tumours by the World Health Organization (WHO) was published in March 2022. In the section on oral cavity and mobile tongue tumours, the classification of epithelial tumours in the 5th edition has ...
LI Jinwei, SHA Tong, ZHENG Kaijuan, NIE Mengdong, GUAN Weihang, SHI Ce   +5 more
doaj   +1 more source

Defining properties of neural crest-derived progenitor cells from the apex of human developing tooth [PDF]

, 2008
The connective tissue of the human tooth arises from cells that are derived from the cranial neural crest and, thus, are termed as "ectomesenchymal cells." Here, cells being located in a pad-like tissue adjacent to the apex of the developing tooth, which
Götz, Werner, Schönebeck, Bodo, Degistirici, Ozer, Siemonsmeier, Jürgen, Martin, Ivan, Jaquiery, Claude, Thie, Michael   +6 more
core