Results 51 to 60 of about 242,337 (233)

Topical Cyclosporine in Thyroid Orbitopathy-Related Dry Eye: Clinical Findings, Conjunctival Epithelial Apoptosis, and MMP-9 Expression

, 2010
Objectives: To evaluate the effects of topical cyclosporine A (CsA) 0.05% (Restasis) on the signs and symptoms of dry eye, on apoptosis, and on MMP-9 expression in conjunctiva epithelial cells in thyroid orbitopathy (TO)-related dry eye ...
Takmaz, Tamer, Canan Gürdal, IŞIK GÖNÜL, İPEK, Özge Saraç, SARAÇ, ÖZGE, Genc, Ipek, Can, Izzet, İpek Gönül, İzzet Can, İpek Genç, Gurdal, Canan, Tamer Takmaz   +11 more
core   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Efficacy and safety of topical cyclosporine 0.05% in vernal keratoconjunctivitis: Aggarwal Eye Hospital, Hyderabad [PDF]

, 2022
Introduction: While corticosteroids are an effective choice of treatment for severe vernal keratoconjunctivitis (VKC), their long-term use is restricted due to side effects.
K.Nitheskumar, K.Sunitha, K.Harinathbabu
core  

The Effects of Topical Cyclosporine 0.05% on Dry Eye Symptoms of Postcataract Surgery

Journal of Medical Sciences
Background: Dry eye disease is a common complication after cataract surgery, often impairing visual recovery and patient satisfaction. Conventional management includes artificial tears and mild corticosteroids, but their efficacy is limited.
Yu-Min Chang, Ke-Hung Chien
doaj   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

THE EFFECT OF COMBINED IMMUNOSUPPRESSION WITH SYSTEMIC LOW-DOSE CYCLOSPORINE AND TOPICAL FLUOCINOLONE ACETONIDE ON THE SURVIVAL OF RAT HINDLIMB ALLOGRAFTS

, 1994
Sixty rat hind-limb allotransplantations across strong histocompatibility barriers were performed. Group I (isograft controls), (Lewis-Brown-Norway [LBN] to LBN) limb transplantations were performed; Group II (rejection controls), LBN limbs transplanted ...
CHICK, L, LISTER, GD, SIEMIONOW, M, INCEOGLU, S, CRAVEN, CM   +4 more
core   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model

, 2013
Purpose: To investigate the effects of topical cyclosporine A 0.05%, cyclosporine A 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% in an experimental allergic conjunctivitis model.
Nigar V., Semsettin B., Sinan E., Semsettin, Bilak, Sinan, Emre, Nigar, Vardi   +5 more
core   +1 more source

Idiopathic Granulomatous Inflammation of the Periocular Structures in Four Dogs: Clinical, Histopathological, and Imaging Findings and Therapeutic Outcome. [PDF]

Vet Ophthalmol
ABSTRACT Purpose To describe cases of canine idiopathic periocular granulomatous inflammation. Material and Methods Clinical records were reviewed. Animal Studied At the time of presentation, the four patients (German Shepherd dog, mixed breed, Magyar Vizsla, Hovawart) were 1.5–5 (mean 3.75) years old. All dogs were female; two were spayed.
Kurwinkel J, Busse C, Beineke A, Gerhauser I, Pahl S, Marx AH.   +5 more
europepmc   +2 more sources

Use of subconjunctival cyclosporine implants for treatment of feline eosinophilic keratoconjunctivitis: A case report

Journal of Feline Medicine and Surgery Open Reports
Case summary: A 5-year-old, neutered male domestic shorthair cat was presented for evaluation of chronic bilateral eosinophilic keratoconjunctivitis (EK).
Lynn Willems, Jordan K. Roberts
doaj   +1 more source