Results 181 to 190 of about 79,811 (267)

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Kedi Wang, Dongjiang Xu, Yan Gao, Wen Zhao, Kaihui Ma   +4 more
wiley   +1 more source

Updates on Antibody Drug Conjugates and Bispecific T-Cell Engagers in SCLC. [PDF]

Antibodies (Basel)
Wang K, Taing K, Hsu R.
europepmc   +1 more source

The Role of Residual Hydrogen Peroxide for Biological Applications of Polymeric N‐Oxides

Journal of Polymer Science, Volume 64, Issue 2, Page 384-394, 15 January 2026.
Polymeric N‐oxides bind hydrogen peroxide with very high affinity. Therefore, residues of the oxidizing agent are difficult to remove from the polymers. This study shows that microbiological studies of polymeric N‐oxides can be compromised by these residues. Conflicting data on the antimicrobial properties of polymeric N‐oxides are therefore likely due
Michelle Kobus, Shirin Mesgarha, Erica Moretto, Jon Wullenweber, Mathias Ernst, Sebastian G. Wicha, Wolfgang Maison   +6 more
wiley   +1 more source

Deciphering RNA and protein expression discordance identifies TOP2A as a prognostic biomarker and potential therapeutic target in lung adenocarcinoma. [PDF]

Discov Oncol
Miyabe M, Arimitsu S, Bolatkan A, Machino H, Hamamoto R, Asada K.   +5 more
europepmc   +1 more source

Anti-cytolethal distending toxin antibodies in systemic sclerosis: associations with gastrointestinal disease and immune dysregulation. [PDF]

Rheumatology (Oxford)
Di Ciommo FR, Casciola-Rosen L, Ayla AY, Balar A, Shah AA, Hughes M, Morales W, Pimentel M, Adler BL, McMahan ZH.   +9 more
europepmc   +1 more source

DNA topoisomerase III from extremely thermophilic archaebacteria. ATP-independent type I topoisomerase from Desulfurococcus amylolyticus drives extensive unwinding of closed circular DNA at high temperature

, 1991
Alexeï Slesarev, D.A. Zaitzev, V. M. Kopylov, Karl O. Stetter, Sergei A. Kozyavkin   +4 more
openalex   +1 more source

Scaffold Simplification Yields Potent Antibacterial Agents That Target Bacterial Topoisomerases. [PDF]

Molecules
Khudiakova L, Komarova K, Zhuravlev M, Deniskin D, Golovanov A, Nichugovskiy A, Babkin K, Zakharova M, Chudinov M, Rogacheva E, Kraeva L, Shevtsova O, Ipatova D, Skvortsov D, Lukianov D, Kryakvin M, Gureev M, Lukin A.   +17 more
europepmc   +1 more source

A novel radiosensitizer α-sulfoquinovosyl-acylpropanediol (SQAP) inhibits DNA repair pathways and sensitize cells to cancer chemotherapeutic agents. [PDF]

Sci Rep
Maeda J, Sunada S, Fukuhara T, Kato TA.
europepmc   +1 more source

Faculty Opinions recommendation of Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.

, 2019
Scott H. Kaufmann
openalex   +2 more sources

Leveraging topoisomerase II-mediated DNA damage: repurposing etoposide as a lead compound for apicomplexan parasite control. [PDF]

Front Vet Sci
Li Y, Cui Z, Li J, Zhang Y, Zafar I, Rizk MA, Li H, El-Sayed SAE, Yokoyama N, Guo Q, Xuan X, Chahan B.   +11 more
europepmc   +1 more source