Results 191 to 200 of about 68,974 (263)

Prime, trap, and fail: engineering chromatin to potentiate topoisomerase II poisons in prostate cancer. [PDF]

Transl Androl Urol
Kwon WA.
europepmc   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Cellular strategies for repairing trapped protein-DNA complexes. [PDF]

Front Pharmacol
Sideridou M, Machli DI, Lontra D, Rampias T.   +3 more
europepmc   +1 more source

Structural interactions of BWC0977 with Klebsiella pneumoniae topoisomerase IV and biochemical basis of its broad-spectrum activity. [PDF]

Commun Biol
Nandishaiah R, Murakami S, Hameed P S, Aoki M, Okada U, Yamashita E, Venkatesan S, Bharatham N, Sarma S, Shanbhag AP, Sharma S, Rao R, Ramachandran V, Balasubramanian V, Datta S, Katagihallimath N.   +15 more
europepmc   +1 more source

The Therapeutic Potential of Stem Cell Therapy for Doxorubicin‐Induced Cardiotoxicity: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent whose clinical utility is significantly constrained by severe side effects, most notably DOX‐induced cardiotoxicity (DIC). Pathophysiological mechanisms of DIC include oxidative stress, mitochondrial dysfunction, programmed cell death, and inflammation ...
Ali Mirzaei, Pouria Rezaei, Reza Golchin Vafa, Saleheh Jahani, Reza Arefnezhad, Hossein Fatemian, Mohammad Hossein Nikoo, Amirhossein Sahebkar, Fatemeh Rezaei‐Tazangi   +8 more
wiley   +1 more source

Evolution and recent advances in antibody-drug conjugate therapy for lung cancer: a comprehensive systematic review based on the Trialtrove database (inception to July 1, 2025). [PDF]

Front Oncol
Chen Y, Zhang Y, Tian C, Li Z, Guo G.
europepmc   +1 more source

Increased sensitivity of etoposide-treated breast cancer cells with an ATM inhibitor. [PDF]

PLoS One
Kumar ARK, Shaji CS, Rajagopalan A, Bhattacharya S, Martínez-López W, Saraswathy R.   +5 more
europepmc   +1 more source

Case Report: Complete response to the novel NaPi2b-targeting ADC YL205 in heavily pretreated platinum-resistant ovarian cancer. [PDF]

Front Oncol
Tang YX, Xiao H, Tang ZZ, Jian L, Guo X.
europepmc   +1 more source

Blue Fluorescent Siloxytecans Exhibit Potent Anticancer Activity and Enable Direct Real-Time Quantification of Intracellular Uptake. [PDF]

ACS Bio Med Chem Au
Lo I, Vaidya S, Mo A, Chia AY, Li K, Parvin J, Sadagopan S, D'souza Z, Kwok O, Zhang J, Baratoff I, Somani S, Menta L, Xie Y, Sanchez T, Wang T, Chen R, Yamamoto A, Pazzi J, Njoo E.   +19 more
europepmc   +1 more source

Total body irradiation and smoking interact to increase lung cancer risk after blood or marrow transplantation. [PDF]

Blood Adv
Balas N, Chen Y, Meng Q, Hageman L, Landier W, Richman J, Bosworth A, Wong FL, Bhatia R, Weisdorf DJ, Armenian SH, Bhatia S.   +11 more
europepmc   +1 more source