Results 271 to 280 of about 146,499 (323)

Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy. [PDF]

Pharmaceuticals (Basel)
Dos Santos JC, Alves JEF, de Azevedo RDS, da Silva JG, Silva MRO, da Silva LPBG, Soares CVS, da Silva JM, da Silva NF, de Oliveira JF, de Lima MDCA, Moura RO, de Almeida SMV.   +12 more
europepmc   +1 more source

Structural modeling and docking analysis of canonical and novel resistance-associated missense mutations in Sudanese Escherichia coli. [PDF]

Sci Rep
Sage EE, Ibrahim SAE, Firdaus-Raih M, Samhoon SOA, Mohamed AAM, Ahmed TME, Saadaldin MM, Suliman OH, Mohamed O, Mohamed SB, Ali QM.   +10 more
europepmc   +1 more source

Deciphering RNA and protein expression discordance identifies TOP2A as a prognostic biomarker and potential therapeutic target in lung adenocarcinoma. [PDF]

Discov Oncol
Miyabe M, Arimitsu S, Bolatkan A, Machino H, Hamamoto R, Asada K.   +5 more
europepmc   +1 more source

Epigenetic Activity of Cancer Therapy Drugs Revealed by HeLa TI Cell-Based Assay. [PDF]

Epigenomes
Maksimova V, Popova V, Kholodova A, Makus J, Usalka O, Lylova E, Kudriashov A, Belitsky G, Yakubovskaya M, Kirsanov K.   +9 more
europepmc   +1 more source

Leveraging topoisomerase II-mediated DNA damage: repurposing etoposide as a lead compound for apicomplexan parasite control. [PDF]

Front Vet Sci
Li Y, Cui Z, Li J, Zhang Y, Zafar I, Rizk MA, Li H, El-Sayed SAE, Yokoyama N, Guo Q, Xuan X, Chahan B.   +11 more
europepmc   +1 more source

Hospital-based first diagnoses of systemic sclerosis: Defining initial clinical presentations and diagnostic pathways. [PDF]

Rheumatol Immunol Res
Luengthanapol T, Onchan T, Pongkulkiat P, Mahakkanukrauh A, Suwannaroj S, Foocharoen C.   +5 more
europepmc   +1 more source

A novel radiosensitizer α-sulfoquinovosyl-acylpropanediol (SQAP) inhibits DNA repair pathways and sensitize cells to cancer chemotherapeutic agents. [PDF]

Sci Rep
Maeda J, Sunada S, Fukuhara T, Kato TA.
europepmc   +1 more source

Molecular dynamics simulations reveal DNA gate opening mechanisms for M. smegmatis topoisomerase 1A. [PDF]

Biophys J
Sigdel D, Mills M.
europepmc   +1 more source

Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidence. [PDF]

PLoS One
Metwaly AM, Eissa IH, Afifi WM, Elkaeed EB, Alsfouk AA, Ibrahim IM, Abdelfattah MS.   +6 more
europepmc   +1 more source