Results 211 to 220 of about 67,641 (348)

Topoisomerase [PDF]

, 2020
openaire   +1 more source

Mitochondrial Transporter ABCB10 Protects Against Doxorubicin‐Induced Respiratory Muscle Dysfunction Independent of Changes to Diaphragm Accumulation

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Doxorubicin (DOX) is a highly effective chemotherapeutic agent whose use can cause respiratory toxicity, increasing patient fatigue and negatively impacting quality of life and survival. These adverse effects occur due to diaphragm muscle mitochondrial accumulation of DOX, where it causes reactive oxygen species production and iron ...
Ashley J. Smuder, Vivian Doerr, Cesar E. Jacintho Moritz, Jie Li, Branden L. Nguyen   +4 more
wiley   +1 more source

Gyrase and Topoisomerase IV as Antibacterial Targets for Gepotidacin and Zoliflodacin: Teaching Old Enzymes New Tricks. [PDF]

Int J Mol Sci
Osheroff N.
europepmc   +1 more source

Topoisomerases and the regulation of neural function

Nature Reviews Neuroscience, 2016
P. Mckinnon
semanticscholar   +1 more source

A DifluorinatedDerivative of ARC-111 Suppresses IntrahepaticCholangiocarcinoma Growth via Targeting Topoisomerase I

Yin-Peng Bai (22032220), Mi Zhang (42795), Jian-Hua Liu (340103), Gui-Sha Chen (22032223), Cheng-Jie Yang (8301990), Nan Deng (428444), Chan-Yuan Chen (22032226), Zhi-Ping Wang (3613484), Chuan-Rui Xu (15084774), Zhi-Jun Zhang (471421), Lei Li (29537), Li-Zeng Peng (12588064), Min Liu (45756), Ying-Qian Liu (1328325)   +13 more
openalex   +1 more source

Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim, Nisreen Salah Majeed, Asmaa A. Salam, Rania Hameed Hamad, Yeganeh Behrouzi, Erta Rajabi, Razieh Shahbazi   +6 more
wiley   +1 more source

Proteomic Analysis of Human Topoisomerases Reveals Their Distinct and Diverse Cellular Functions. [PDF]

Mol Cell Proteomics
Zhang H, Xiong Y, Chen Z, Chen J.
europepmc   +1 more source

Topoisomerase I inhibitors: camptothecins and beyond [PDF]

, 2006
Yves Pommier
openalex   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

Processing of DNA Topoisomerase II-DNA-Protein Crosslinks Associated With Anticancer Drugs. [PDF]

Genes Cells
Sakasai R, Iwabuchi K.
europepmc   +1 more source