Results 61 to 70 of about 329,929 (341)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Research on Strategy of DC Micro-grid Control and Protection

open access: yes南方能源建设, 2020
[Introduction] The control and protection technology of DC microgrid plays an important role in ensuring the reliable and safe operation of DC microgrid. The paper aims to solve the key technologies in the design of DC micro-grid.
ZHOU Yu   +4 more
doaj   +1 more source

Computing the topology of configuration space [PDF]

open access: yes[Proceedings] 1992 IEEE International Conference on Systems, Man, and Cybernetics, 2003
The problem of planning collision-free paths for manipulators is considered. An algorithm is presented for generating the connectivity graph for a class of articulated manipulators. The algorithm is based upon the ability to determine whether two distinct obstacles in configuration space intersect.
J.J. Fox, A.A. Maciejewski
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Topology-Aware Bus Routing in Complex Networks of Very-Large-Scale Integration with Nonuniform Track Configurations and Obstacles

open access: yesComplexity, 2021
As one of the most important routing problems in the complex network within a very-large-scale integration (VLSI) circuit, bus routing has become much more challenging when witnessing the advanced technology node enters the deep nanometer era because all
Ziran Zhu   +3 more
doaj   +1 more source

A New Configuration of Nine-Level Boost Inverter with Reduced Component Count

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy, 2021
The single-stage boost inverter configuration is an essential system for renewable energy applications. In this paper, a new nine-level inverter topology with a step-up feature has been presented and discussed in detail.
Marif Daula Siddique, Saad Mekhilef
doaj   +1 more source

A middleware framework for constraint-based deployment and autonomic management of distributed applications [PDF]

open access: yes, 2004
Submitted to Middleware 04 Funded by the EPSRC UK grant GR/S44501 "Secure LocationIndependent Autonomic Storage Architectures"We propose a middleware framework for deployment and subsequent autonomic management of component-based distributed applications.
Dearle, Alan   +2 more
core   +4 more sources

Comprehensive Analysis of Microgrids Configurations and Topologies [PDF]

open access: gold, 2022
Katherine Cabana-Jiménez   +2 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Topology optimization analysis of VLCC transverse web based on UNet deep learning

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveThis paper proposes a hull transverse web topology optimization method based on UNet for application in the optimization design of complex ship structures.
Zhenrong LI, Lijuan XIA, Shuo FENG
doaj   +1 more source

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