Results 131 to 140 of about 12,036,872 (292)

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

British Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen, Ngoc Hoang Le, Nhu Quynh Phan, Toan Trung Duong, Le Thi Anh Thu, Hsuan‐Chia Yang, Chih‐Wei Huang, Min‐Huei Hsu, Jason C. Hsu, Chien‐Tien Su, Phung‐Anh Nguyen   +10 more
wiley   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Multifunctional polycaprolactone‐based composite fibers with icariin and glutathione for effective repair of critical‐sized bone defects

BMEMat, EarlyView.
A multifunctional PCL‐based scaffold co‐delivering Icariin and Glutathione synergistically enhances osteogenesis, angiogenesis, and oxidative stress resistance, achieving near‐complete repair of critical‐sized bone defects in vivo. This cell‐free platform represents a promising strategy for accelerated bone regeneration.
Abdurohman Mengesha Yessuf, Yaqi Zhang, Bharat Prasad Sharma, Yake Wang, Tibebu Shiferaw Kassa, Abdul Qadir, Ye Jinqiu, Mohamedazeem M. Mohideen, Ahmed M. Salama, Weiguo Wang, Qidong Zhang, Yong Liu   +11 more
wiley   +1 more source

Monofloral Features of Turkish Honeys According to Melissopalynologic, Total Phenolic and Total Flavonoid Content

, 2018
The main objective of this study was to evaluate the plant composition of honey from different part of Turkey. Within this scope, melissopalynological characterizations, total phenolic and total flavonoid content were determined of 28 honey samples.
ÖZENİRLER, ÇİĞDEM, Canli, Deniz, Sorkun, Kadriye, ÖZKÖK, ASLI, Mayda, Nazli   +4 more
core  

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source

Optimization of Soxhlet extraction conditions for total phenolic content, total flavonoid content, and DPPH radical-scavenging activity of neem (

South African Journal of Chemical Engineering
Neem ( Azadirachta indica ) is widely known for its rich source of bioactive compounds such as phenolics and flavonoids that exhibit strong antioxidant and therapeutic properties.
Crystal Hui Man Tiong, Nurizzati Md Daud, Hassan Fahmi Ismail, Fadzilah Adibah Abd Majid, Ismail Ware, Nur Syukriah Ab Rahman   +5 more
doaj   +1 more source

Free radical scavenging potential and total phenolic and flavonoid content of Ziziphus mauritiana and Ziziphus nummularia fruit extracts

, 2012
Free radical scavenging potential and total phenolic and flavonoid content of Ziziphus mauritiana and Ziziphus nummularia fruit ...
AG Dureja (15803516), K Dhiman (14466744)   +1 more
core  

Processing‐Induced Changes in Bioactive Compounds, Physicochemical, Nutritional, and Sensory Properties of Asian Salted Noodles Fortified With Red Beetroot Flour

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Asian salted noodles (ASN) are popular in East and Southeast Asia and in parts of Europe and the Americas. However, ASN are deficient in certain nutrients (e.g., vitamins, minerals, and dietary fiber) and bioactive compounds.
Gia Ngoc Lam, Fan Zhu
wiley   +1 more source

α-Glucosidase inhibitory flavonoids of Actinidia arguta fruits: Comparison of different cultivars

Folia Horticulturae
Actinidia arguta (Siebold & Zucc.) Planch. ex Miq. is one of the major species of the genus Actinidia and has distinct characteristics such as small size and smooth-fruited. The fruits of A. arguta are rich in essential nutrients and bioactive compounds.
Ryu Se Hwan, Lee Hak Hyun, Ahn Jong Hoon, Turk Ayman, Park Youngki, Kim Seon Beom, Hwang Bang Yeon, Lee Mi Kyeong   +7 more
doaj   +1 more source