Results 91 to 100 of about 136,864 (311)

Drynaria total flavonoids decrease cathepsin K expression in ovariectomized rats

Genetics and Molecular Research, 2014
This study investigated the effects of Drynaria total flavonoids on cathepsin K serum concentrations and gene expression, biomechanics and bone mineral density (BMD) of the tibial shaft in ovariectomized rat models of osteoporosis, and mechanism in the prevention and cure of osteoporosis.
X L, Shi, C W, Li, Q Z, Wan, A Q, Li, H, Wang, K, Liu   +5 more
openaire   +2 more sources

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Determination of Total Polysaccharides and Total Flavonoids in Chrysanthemum morifolium Using Near-Infrared Hyperspectral Imaging and Multivariate Analysis

Molecules, 2018
The rapid and nondestructive determination of active compositions in Chrysanthemum morifolium (Hangbaiju) is of great value for producers and consumers.
Juan He, Lidan Chen, Bingquan Chu, Chu Zhang   +3 more
doaj   +1 more source

Regulation of Cbfa1 Expression by Total Flavonoids of Herba Epimedii

Endocrine Journal, 2006
Core binding factor alpha1 (Cbfa1) is a member of the runt family of transcription factors, which appears to play a pivotal role in regulating the differentiation of osteoblastic precursors and the activity of mature osteoblasts. Total flavonoids of Herba epimedii (HEF) is a recognized bone anabolic agent, but there is lack of reports on the modulation
Guofeng, Qian, Xiuzhen, Zhang, Lixia, Lu, Xinjiang, Wu, Shumei, Li, Jian, Meng   +5 more
openaire   +3 more sources

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Integrated Experimental and Theoretical Insights into Defect‐Induced Functionalities of Cobalt Doped NiO for Multifunctional Solar‐Driven Applications

Advanced Energy and Sustainability Research, EarlyView.
Rational defect engineering in Co‐doped NiO nanostructures, synthesized via a sustainable green route, enables precise bandgap modulation and defect‐state tailoring. Combined experimental–density functional theory analysis identifies 15% Co doping as the optimal threshold for maximizing photocatalytic degradation, photothermal response, and hydrogen ...
Sumayya M. Ansari, Hessa Alashkhari, Meira Alabdouli, Zahra Alzadjali, Sara Almuhairi, Narender Kumar, Naveen Kosar, Tariq Mahmood, Adnan Younis   +8 more
wiley   +1 more source

Zinc Oxide Nanoparticles Boosts Phenolic Compounds and Antioxidant Activity of Capsicum annuum L. during Germination

Agronomy, 2018
The effects of zinc oxide nanoparticles on seed germination and seedling growth of Capsicum annuum L. were determined in this research. Total phenols content, total flavonoids, and condensed tannins, as well as 2,2-diphenyl-1-picrylhydrazyl (DPPH ...
Josué I. García-López, Francisco Zavala-García, Emilio Olivares-Sáenz, Ricardo H. Lira-Saldívar, Enrique Díaz Barriga-Castro, Norma A. Ruiz-Torres, Edith Ramos-Cortez, Rigoberto Vázquez-Alvarado, Guillermo Niño-Medina   +8 more
doaj   +1 more source

Bakery Products Enriched With Fruit and Vegetable Wastes: A Functional Approach

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Enrichment of bakery products with bioactive compounds from fruit and vegetable wastes. ABSTRACT Bread and other bakery goods are among the most critical components of the human diet, which make them attractive carriers for functional ingredients aimed at improving public health.
Sena Bakir
wiley   +1 more source

Identification of miRNA and Their Regulatory Effects Induced by Total Flavonoids From Dracocephalum moldavica in the Treatment of Vascular Dementia [PDF]

, 2021
Mimin Liu, Guangzhi Shan, Hailun Jiang, Li Zeng, Kaiyue Zhao, Yiran Li, Ghulam Md Ashraf, Zhuorong Li, Rui Liu   +8 more
openalex   +1 more source