Results 31 to 40 of about 8,795,233 (257)

Response to Neoadjuvant Therapy and Prognosis in Patients with Resectable Pancreatic Cancer: A Propensity Score Matching Analysis

Gut and Liver, 2022
Background/Aims: Controversy regarding the effectiveness of neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma (PDAC) still exists.
Min Sung Yoon, Hee Seung Lee, Chang Moo Kang, Woo Jung Lee, Jiyoung Keum, Min Je Sung, Seung-seob Kim, Mi-Suk Park, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Ho Kyoung Hwang, Seungmin Bang   +14 more
doaj   +1 more source

The Predictors of Complete Pathologic Response in Rectal Cancer during the Total Neoadjuvant Therapy Era: A Systematic Review

, 2023
The modern rectal cancer treatment paradigm offers additional opportunities for organ preservation, most notably via total neoadjuvant therapy (TNT) and consideration for a watch-and-wait (WW) surveillance-only approach.
Ira L. Leeds, Haddon J. Pantel, Kurt S. Schultz, Emily Flom   +3 more
core   +1 more source

Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

, 2013
AIM: To assess tumour regression grade (TRG) and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS: Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal ...
Kelly, Jamie, Iveson, T., Underwood, T.J., Rees, Charlotte, Bailey, Ian, Bateman, Andrew R., Byrne, James, Sharland, Donna, Noble, Fergus, Bateman, Adrian C., Nolan, Luke   +10 more
core   +1 more source

Surgical Considerations for Neoadjuvant Therapy for Pancreatic Adenocarcinoma

, 2023
Pancreatic ductal adenocarcinoma (PDAC) is a challenging disease process with a 5-year survival rate of only 11%. Neoadjuvant therapy in patients with localized pancreatic cancer has multiple theoretical benefits, including improved patient selection for
Anish J. Jain, Matthew H. G. Katz, Jessica E. Maxwell, Rebecca A. Snyder   +3 more
core   +1 more source

Controversies and Perspectives in the Current Management of Patients with Locally Advanced Rectal Cancer—A Systematic Review

Life
Traditionally, the therapeutic approach to rectal cancer has involved neoadjuvant chemoradiotherapy followed by surgical resection, and, in some cases, adjuvant chemotherapy.
Roxana Elena Stefan, Rodica Daniela Birla, Mircea Gheorghe, Daniela Elena Dinu, Petre Angel Hoara, Diana Ciuc, Valeriu-Gabi Dinca, Silviu Constantinoiu   +7 more
doaj   +1 more source

Comparing outcomes following total neoadjuvant therapy and following neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer

EClinicalMedicine, 2019
Background: There is recent interest in treating locally advanced rectal cancer (LARC) patients with total neoadjuvant therapy (TNT). However, whether TNT is associated with improved overall survival (OS) remains unknown.
Shaoyu Zhu, N. Patrik Brodin, Keara English, Nitin Ohri, Jennifer W. Chuy, Lakshmi N. Rajdev, Rahul Narang, Shalom Kalnicki, Chandan Guha, Madhur K. Garg, Rafi Kabarriti   +10 more
doaj   +1 more source

The effects of neoadjuvant zoledronic acid in breast cancer patients: A meta-analysis of randomized controlled trials

Asian Journal of Surgery, 2023
To explore the effects of Zoledronic acid (ZA) in the neoadjuvant setting, we conducted a meta-analysis of randomized controlled trials (RCTs) of neoadjuvant therapy with or without ZA in breast cancer (BC). A systematic literature search was carried out
Mei Liu, Shengqiang Qian, Jing Wu, Jing Xiao, Xiaohua Zeng   +4 more
doaj   +1 more source

Retrospective Evaluation of the Efficacy of Total Neoadjuvant Therapy and Chemoradiotherapy Neoadjuvant Treatment in Relation to Surgery in Patients with Rectal Cancer

Medicina
Background and Objective: In the therapeutic strategy of rectal cancer, radiotherapy has consolidated its important position and frequent use in current practice due to its indications as neoadjuvant, adjuvant, definitive, or palliative treatment.
Lucian Dragoș Bratu, Michael Schenker, Puiu Olivian Stovicek, Ramona Adriana Schenker, Alina Maria Mehedințeanu, Tradian Ciprian Berisha, Andreas Donoiu, Stelian Ștefăniță Mogoantă   +7 more
doaj   +1 more source

Total neoadjuvant therapy for locally advanced rectal cancer: a narrative review [PDF]

, 2023
Locally advanced rectal cancer has traditionally been treated with chemoradiotherapy (CRT) followed by surgery and adjuvant chemotherapy. However, a new strategy, total neoadjuvant therapy, involves the administration of CRT and neoadjuvant chemotherapy ...
Paula Peleteiro Higuero, Domínguez, María Mateos, Mateos, Raquel Fuentes, Gomis Sellés, Elías, Macías, Virginia Morillo, Raquel Fuentes Mateos, Peleteiro Higuero, Paula, Fuentes Mateos, Raquel, Virginia Morillo Macías, González Del Portillo, Elisabet, Daniela Gonsalves Pieretti, Couñago, Felipe, López-Campos, Fernando, Ferraris, Gustavo, Sellés, Elías Gomis, Higuero, Paula Peleteiro, Ana Aurora Díaz-Gavela, Gustavo Ferraris, Elisabet González Del Portillo, Del Portillo, Elisabet González, Fernando Lopez Campos, Felipe Couñago, Pieretti, Daniela Gonsalves, Elías Gomis Sellés, Gonsalves Pieretti, Daniela, Díaz-Gavela, Ana Aurora, María Mateos Domínguez, Mateos Domínguez, María, Morillo Macías, Virginia, Campos, Fernando Lopez   +29 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source