Results 201 to 210 of about 3,633,346 (267)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source
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Assays for Total Protein

Current Protocols in Microbiology, 1995
AbstractThis unit describes three copper‐based assays to quantitate total protein: the biuret method, a variation of the Lowry method (Hartree‐Lowry method), and the bicinchoninic acid (BCA) assay. Acid hydrolysis of a protein is coupled with ninhydrin detection to quantitate amino acid content of a sample.
Rex, Lovrien, Daumantas, Matulis
openaire   +2 more sources

The Total Protein of Human Perilymph

Acta Oto-Laryngologica, 1969
Total protein values were determined from the perilymph of 47 cadaver ears. After subtraction of hemoglobin the average total protein for two series of 27 and 10 ears was 553 and 559 mg%, respectively. When the perilymph specimens were taken directly without freezing the average total protein figures were reduced to 280 (cochlea) or 312 mg% (vesti ...
T, Palva, V, Raunio
openaire   +2 more sources

Relationship of Serum Total Calcium to Albumin and Total Protein in Dogs

Journal of the American Veterinary Medical Association, 1982
SUMMARY A positive linear relationship was found between total calcium and albumin and between total calcium and total protein in the serum of 209 dogs. Total calcium concentration correlated with the concentration of albumin (r=0.575; P<0.001) and with the concentration of total protein (r= 0.411; P<0.001).
D J, Meuten   +3 more
openaire   +2 more sources

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