Results 251 to 260 of about 14,944,148 (406)

Total synthesis of (-)-Paeonisuffrone mono- and diacetate

, 2011
Elisabeth Felbermair
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Total Synthesis of the Nominal Structure of (+)-Talaromyolide D. [PDF]

J Am Chem Soc
Qin B, Szyperek A, Tomanik M.
europepmc   +1 more source

A Concise Total Synthesis of the Lichen Macrolide (+)‐Aspicilin.

, 2007
Christophe Dubost, István E. Markó, Thomas Ryckmans   +2 more
openalex   +2 more sources

Enantioselective Total Synthesis of Nigelladine A via Late-Stage C-H Oxidation Enabled by an Engineered P450 Enzyme.

Journal of the American Chemical Society, 2017
Steven A. Loskot, D. K. Romney, F. Arnold, B. Stoltz   +3 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Ni-promoted reductive cyclization cascade enables a total synthesis of (+)-aglacin B. [PDF]

Beilstein J Org Chem
Yao SC, Cao JS, Xiao J, Wang YW, Peng Y.
europepmc   +1 more source

Total Synthesis and Evaluation of Cytostatin, Its C10−C11 Diastereomers, and Additional Key Analogues:  Impact on PP2A Inhibition

, 2006
Brian G. Lawhorn, Sobhana Babu Boga, S. E. Wolkenberg, David A. Colby, Carla‐Maria Gauss, Mark R. Swingle, Lauren Amable, Richard E. Honkanen, Dale L. Boger   +8 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Total Synthesis of (-)-Neocucurbol C Enabled by Pattern Recognition and MHAT Cyclization. [PDF]

J Am Chem Soc
Zhong LP, Gudeman C, Zhen J, Wanasinghe OA, Hellmig J, Collins MJE, Bacsa J, Adibekian A, Dai M.   +8 more
europepmc   +1 more source