Results 261 to 270 of about 3,850,300 (360)

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Total Synthesis of Kavaratamides A-C and Unnatural Analogs. [PDF]

ACS Omega
Berida TI, Lindsley CW.
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Total synthesis of zwitterionic PS A2 oligosaccharides from <i>Bacteroides fragilis</i>. [PDF]

Sci Adv
Li X, Pan-Gao Q, Wan Y, Zeng F, Qi J, Tu Y, Wang L, Wang Z, Codée JDC, Zhang Q.   +9 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Biomimetic Total Synthesis of Dispirocochlearoids A-C and Related <i>Ganoderma</i> Meroterpenoid Dimers. [PDF]

Org Lett
Shi SJ, Liu XL, Yang L, Zhan DS, Chen LH, Yin JP, Nan FJ.   +6 more
europepmc   +1 more source

Enantioselective Total Synthesis of Tricyclic Myrmicarin Alkaloids

, 2005
Mohammad Movassaghi, Alison E. Ondrus
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Total Synthesis of Kanamycins. [PDF]

Chemistry
Hosomi K, Imai B, Takemura N, Senoo K, Hayashi C, Igarashi M, Toshima K, Takahashi D.   +7 more
europepmc   +1 more source

Total synthesis of the lycopodium alkaloid dl-serratinine.

, 1975
Takashi Harayama, Mitsuaki Ohtani, M. OKI, Yasuo Inubushi   +3 more
openalex   +2 more sources