Results 281 to 290 of about 16,454,265 (355)

Total Synthesis of Darobactin A.

Journal of the American Chemical Society, 2022
The collaborative total synthesis of darobactin A, a recently isolated antibiotic that selectively targets Gram-negative bacteria, has been accomplished in a convergent fashion with a longest linear sequence of 16 steps from d-Garner's aldehyde and l ...
M. Nešić, David B. Ryffel, Jonathan Maturano, M. Shevlin, Scott R Pollack, D. Gauthier, Pablo Trigo-Mourino, Li-Kang Zhang, Danielle M. Schultz, Jamie M. McCabe Dunn, Louis-Charles Campeau, Niki R. Patel, David A Petrone, D. Sarlah   +13 more
semanticscholar   +1 more source

Asymmetric Total Synthesis of Taxol.

Journal of the American Chemical Society, 2021
Taxol is one of the most famous natural diterpenoids and an important anticancer medicine. Taxol represents a formidable synthetic challenge and has prompted significant interest from the synthetic community.
Ya-Jian Hu, Chengyun Gu, Xin-Feng Wang, Long Min, Chuang-Chuang Li   +4 more
semanticscholar   +1 more source

Divergent Strategy in Natural Product Total Synthesis.

Chemical Reviews, 2018
Lei Li, Zhuang Chen, Xiwu Zhang, Yanxing Jia   +3 more
semanticscholar   +3 more sources

Time and Pot Economy in Total Synthesis.

Accounts of Chemical Research, 2021
ConspectusWe would all like to make or obtain the materials or products we want as soon as possible. This is human nature. This is true also for chemists in the synthesis of organic molecules.
Y. Hayashi
semanticscholar   +1 more source

Construction of sulfur-containing moieties in the total synthesis of natural products.

Natural product reports (Print), 2020
Covering: January 2013 to September 2018Sulfur-containing natural products are a large class of significant functional molecules. Many of these compounds exhibit potent biological activities and pharmacological properties; in fact, some of them have been
Nengzhong Wang, Puli Saidhareddy, Xuefeng Jiang   +2 more
semanticscholar   +1 more source

Time Economy in Total Synthesis.

Journal of Organic Chemistry, 2020
It is often said that "time is money". This is certainly true in a multistep synthesis when a high-valued product or set of products is needed urgently. Fulfilling this need requires the sensible balancing of atom economy, step economy, and redox economy
Y. Hayashi
semanticscholar   +1 more source

Modular Total Synthesis in Reticular Chemistry.

Journal of the American Chemical Society, 2020
The idea of modularity in organic total synthesis has promoted the construction of diverse targeted natural products by varying the building blocks and assembly sequences.
Liang Feng, Kun-Yu Wang, Xiu‐Liang Lv, Tian-Hao Yan, Jianrong Li, Hongcai Zhou   +5 more
semanticscholar   +1 more source

Total Synthesis of (-)-Rhodomollanol A.

Journal of the American Chemical Society, 2020
An asymmetric approach for the first total synthesis of (-)-rhodomollanol A, a highly oxidized diterpenoid, is described. The efficient synthetic strategy features three key transfor-mations: 1) an oxidative dearomatization-induced (5+2) cy-cloaddition ...
Jianhong Gao, P. Rao, Kaixiang Xu, Shuaifeng Wang, Yufei Wu, Chi He, H. Ding   +6 more
semanticscholar   +1 more source

Total synthesis of (−)-raumacline

Chem. Commun., 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Bailey, Patrick D., Clingan, Paul D., Mills, Timothy J., Price, Richard A., Pritchard, Robin G.   +4 more
openaire   +2 more sources