Results 41 to 50 of about 10,628 (259)

On totally nonpositive matrices associated with a triple negatively realizable [PDF]

open access: yes, 2021
[EN] Let A is an element of R-nxn be a totally nonpositive matrix (t.n.p.) with rank r and principal rank p, that is, every minor of A is nonpositive and p is the size of the largest invertible principal submatrix of A.
Cantó Colomina, Rafael   +2 more
core   +1 more source

Superregular Matrices over Finite Fields

open access: yesMathematics
A trivially zero minor of a matrix is a minor having all its terms in the Leibniz formula equal to zero. A matrix is superregular if all of its minors that are not trivially zero are nonzero.
Paulo Almeida   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Square matrices with the inverse diagonal property

open access: yesKuwait Journal of Science
We identify the class of real square invertible matrices A for which the signs of the diagonal entries of A−1 match those of A, and begin their study. We say such matrices have the inverse diagonal property (IDP).
Susana Furtado   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Q-system Cluster Algebras, Paths and Total Positivity

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
In the first part of this paper, we provide a concise review of our method of solution of the A_r Q-systems in terms of the partition function of paths on a weighted graph. In the second part, we show that it is possible to modify the graphs and transfer
Philippe Di Francesco, Rinat Kedem
doaj   +1 more source

Total positivity of recursive matrices

open access: yesLinear Algebra and its Applications, 2015
Let $A=[a_{n,k}]_{n,k\ge 0}$ be an infinite lower triangular matrix defined by the recurrence $$a_{0,0}=1,\quad a_{n+1,k}=r_{k}a_{n,k-1}+s_{k}a_{n,k}+t_{k+1}a_{n,k+1},$$ where $a_{n,k}=0$ unless $n\ge k\ge 0$ and $r_k,s_k,t_k$ are all nonnegative. Many well-known combinatorial triangles are such matrices, including the Pascal triangle, the Stirling ...
Chen, Xi, Liang, Huyile, Wang, Yi
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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