Results 61 to 70 of about 5,438,961 (250)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Q-system Cluster Algebras, Paths and Total Positivity

Symmetry, Integrability and Geometry: Methods and Applications, 2010
In the first part of this paper, we provide a concise review of our method of solution of the A_r Q-systems in terms of the partition function of paths on a weighted graph. In the second part, we show that it is possible to modify the graphs and transfer
Philippe Di Francesco, Rinat Kedem
doaj   +1 more source

Total positivity of recursive matrices

Linear Algebra and its Applications, 2015
Let $A=[a_{n,k}]_{n,k\ge 0}$ be an infinite lower triangular matrix defined by the recurrence $$a_{0,0}=1,\quad a_{n+1,k}=r_{k}a_{n,k-1}+s_{k}a_{n,k}+t_{k+1}a_{n,k+1},$$ where $a_{n,k}=0$ unless $n\ge k\ge 0$ and $r_k,s_k,t_k$ are all nonnegative. Many well-known combinatorial triangles are such matrices, including the Pascal triangle, the Stirling ...
Chen, Xi, Liang, Huyile, Wang, Yi
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A probabilistic representation of totally positive matrices [PDF]

, 1986
C. Loewner (Math. Z. 63 (1955), 338–340) has shown that every non-singular totally positive matrix of finite order can be reached from the identity by forward solutions of the control equation dRdt = C(t)R, when C(t) varies in the class of Jacobi ...
Goodman, Gerald S
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The LU-factorization of totally positive matrices [PDF]

, 1973
An n × n real matrix A is an STP (strictly totally positive) matrix if all its minors are strictly positive. An n × n real triangular matrix A is a ΔSTP matrix if all its nontrivial minors are strictly positive. It is proved that A is an STP matrix iff A
Colin W. Cryer, Cryer, Colin W.
core   +1 more source

On Totally Geodesic Submanifolds

Axioms
We give a proof of Cartan’s Theorem on totally geodesic submanifolds for real analytic manifolds endowed with a real analytic, torsion-free, affine connection. We apply the theorem to real analytic Hadamard manifolds and, more generally, to real analytic
Antonella Nannicini, Donato Pertici
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Coherence Matrix Estimation With Total Positivity Regularization for Interferometric Phase Linking

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Interferometric phase linking has become a critical step in distributed scatterer interferometry, yet its performance is significantly affected by inaccuracies in the coherence matrix and its inverse, such as the precision matrix.
Changjun Zhao, Yan Yan, Hanwen Yu
doaj   +1 more source