Results 51 to 60 of about 5,438,961 (250)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
AxiomsThe approach to solving linear systems with structured matrices by means of the bidiagonal factorization of the inverse of the coefficient matrix is first considered in this review article, the starting point being the classical Björck–Pereyra algorithms
José-Javier Martínez
doaj +1 more source
Gaussian Markov Random Fields and totally positive matrices
Journal of Computational and Applied Mathematics, 2023 This research was partially supported through the Spanish research grant PGC2018-096321-B-I00 (MCIU/AEI), Gobierno de Aragón, Spain (E41_20R) and the Spanish Ministry of Science and Technology (TIN-2017-87600-P)
Juan Baz +3 more
openaire +4 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Superregular Matrices over Finite Fields
MathematicsA trivially zero minor of a matrix is a minor having all its terms in the Leibniz formula equal to zero. A matrix is superregular if all of its minors that are not trivially zero are nonzero.
Paulo Almeida +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Square matrices with the inverse diagonal property
Kuwait Journal of ScienceWe identify the class of real square invertible matrices A for which the signs of the diagonal entries of A−1 match those of A, and begin their study. We say such matrices have the inverse diagonal property (IDP).
Susana Furtado +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Surjectivity and invertibility properties of totally positive matrices [PDF]
, 1982 A new “finite section” type theorem is used to show that the members of an interesting class of bounded totally positive matrices map l∞ onto l∞ if and only if their range contains a vector which alternates in sign and has coordinates bounded away from ...
Demko, Stephen
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source