Results 91 to 100 of about 15,449 (239)

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source

Neurosarcoidose: orientações para o neurologista geral [PDF]

, 2012
Neurosarcoidosis (NS) more commonly occurs in the setting of systemic disease. The diagnosis is based on a clinical history suggestive of NS, presence of noncaseating granulomas, and supportive evidence of sarcoid pathology, laboratory, and imaging ...
Abrahão, Agessandro, Barsottini, Orlando Graziani Povoas, Braga-neto, Pedro, Dutra, Lívia Almeida, Oliveira, Ricardo Araújo, Pedroso, José Luiz   +5 more
core   +2 more sources

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Update on ocular toxicity of ethambutol

African Vision and Eye Health, 2016
The purpose of this review is to update clinicians on available literature on the ocular toxicity of ethambutol and the type of eye care to be provided to patients treated with these medications. Ethambutol is a commonly used first-line anti-tuberculosis
Priscilla Makunyane, Solani Mathebula
doaj   +1 more source

Rapidly developing Optic Neuritis secondary to Ethambutol: possible mechanism of injury [PDF]

, 2005
Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months.
Ali, Sajjad, Usman, Uzma, Wasay, Mohammad   +2 more
core   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Antiretroviral therapy-induced Leber’s hereditary optic neuropathy

Southern African Journal of HIV Medicine, 2014
Optic neuropathy in HIV-infected patients results from the HIV infection itself, post-infectious auto-immune disease, opportunistic infections and drugs.
Anand Moodley, Sudika Bhola, Fierdoz Omar, Jade Mogambery   +3 more
doaj   +1 more source

Serum homocysteine, vitamin B 12 and folic acid levels in different types of glaucoma [PDF]

, 2006
Background This study was performed to compare levels of serum homocysteine (Hcy), vitamin B12 and folic acid in patients with primary open-angle glaucoma (POAG), pseudoexfoliative glaucoma (PEXG), normotensive glaucoma (NTG) and healthy controls ...
Tongabay Cumurcu, Semsettin Sahin, Erdinc Aydin, J Flammer, SS Hayreh, V Bousse, M Cahill, P Pianka, A Lowenstein, BA Brown, JD Finkelstein, PM Ueland, MJ Stampfer, IJ Perry, AA Warsi, F Leblhuber, S Bleich, I Leibovitch, RM Vessani, T Puustjarvi, O Altintas, G Wang, T Brunelli, GJ Hankey, GJ Hankey, Z Bagi, GG Koliakos, BA Sela, N Asano, K Karjalainen, C Cursiefen, p Mitchell, S Schumacher, LP Repo   +33 more
core   +1 more source

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares, Jacy Bezerra Parmera, Pedro Augusto Sampaio Rocha‐Filho   +2 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source