Results 81 to 90 of about 16,960 (297)
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies.
Marcus Dörr (112711) +17 more
core +1 more source
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley +1 more source
Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30
Staphylococcus aureus clonal complex CC30 has caused infectious epidemics for more than 60 years, and therefore provides a model system to evaluate how evolution has influenced the disease potential of closely related strains. In previous multiple genome
Martin John Mcgavin +2 more
doaj +1 more source
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies.
Marcus Dörr (112711) +17 more
core +1 more source
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Toxic Shock Syndrome Toxin-1-producing Staphylococcus aureus Bacteremia and Exanthematous and Purpuric Disease with Leukocytoclastic Vasculitis in an Infant [PDF]
Staphylococcus aureus exotoxin toxic shock syndrome toxin-1 (TSST-1) can cause a wide spectrum of immunopathological conditions, from toxic shock syndrome (TSS), a life-threatening illness, to neonatal TSS-like exanthematous disease (NTED), a self ...
Shirakawa, Toshihiko +7 more
core +2 more sources
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun +4 more
wiley +1 more source
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies.
Marcus Dörr (112711) +35 more
core +1 more source
Effects of Total Body Irradiation and Cyclosporin A on the Lethality of Toxic Shock Syndrome Toxin–1 in a Rabbit Model of Toxic Shock Syndrome [PDF]
Toxic shock syndrome (TSS) may be mediated by superantigen-activated T cells, a theory we tested in rabbits, which are more susceptible to the lethal effects of superantigens, such as TSS toxin-1 (TSST-1), than are mice. Rabbits exposed to 10 cGy of total body irradiation exhibited T cell deficiency, with profound depletion of splenic lymphocytes and ...
Martin M, Dinges +4 more
openaire +2 more sources

