Results 101 to 110 of about 16,960 (297)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

DataSheet_3_Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus.pdf

, 2023
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies.
Marcus Dörr (112711), Stephan Michalik (1997962), Matthias Nauck (112743), Nele Friedrich (329201), Cedric Mahncke (16927644), Stefanie Samietz (300852), Tanja C. Meyer (7054115), Barbara M. Bröker (8786336), Georg Homuth (110202), Stefan Weiss (1474864), Stephan B. Felix (112722), Silva Holtfreter (252366), Clemens Cammann (3479999), Hans J. Grabe (10136830), Christian Kohler (655546), Frieder Schmiedeke (16927641), Uwe Völker (112748), Henry Völzke (64286)   +17 more
core   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

A case of toxic shock syndrome(TSS) confirmed by demonstration of toxic shock syndrome toxin-1(TSST-1) in the serum.

Nihon Naika Gakkai Zasshi, 1988
患者は55才の男性でショック状態で入院となった.入院時の体温は41°Cで脈拍は触知せず,眼瞼結膜の充血著明で躯幹の紅皮症,上腹部圧痛および筋痛がみられた.検査所見は急激な重症感染症,腎不全,筋障害,肝障害を示唆した.敗血症性ショックを疑い血液培養,尿培養,便培養,髄液培養,咽頭培養を頻回に行なったが全て陰性であった.抗生物質,コルチコステロイド,ドーパミン,ドブタミン,ノルアドレナリン等の薬物投与により,患者は回復し約1カ月の経過で後遺症を残さず退院した.症状および検査所見から本例はtoxic shock syndrome (TSS)の診断基準を十分に満足した.また血中よりTSST-1をRPLA法で証明した.診断基準を満足し,ブドウ球菌は培養にて陰性で,かつ血中より直接TSST ...
MIHARA, Junji, ASAKURA, Takeshi, MORIUCHI, Masahito, KOJIMA, Hiroyuki, MAKI, Masahiro, SAITOH, Satoshi, SHIRATSUTI, Toshiaki, IGARASHI, Hideo   +7 more
openaire   +3 more sources

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

Exploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen, Wenzhe Yi, Rongzhang Li, Shuangshuang Hu, Xindi Qian, Dan Yan, Qian Zou, Guanru Wang, Yaping Li   +8 more
wiley   +1 more source

Bacterial Toxins: Friends or Foes?

Emerging Infectious Diseases, 1999
Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt, Karen C. Meysick, Alison D. O'Brien   +2 more
doaj   +1 more source

Upcycling Pomegranate Peel Into Functional Yoghurt: Chemical Profile, Antioxidant Capacity, and Anti–Staphylococcus aureus Activity

Food Safety and Health, EarlyView.
Pomegranate peel extract enhanced the nutritional, physicochemical, and microbiological qualities of yoghurt. It is a rich source of polyphenolic compounds that eliminates Staphylococcus aureus in yoghurt at 0.1% and 0.3% concentrations without altering its pH value. ABSTRACT The use of natural additives, particularly pomegranate peel extract (PPE), to
Youmna Maghraby, Aml S. Ibrahim, Ola Wagih Hegab, Hamdy A. Zahran, Eman F. Abdel‐Latif   +4 more
wiley   +1 more source

Presence of Staphylococcus aureus enterotoxin genes in milk and dairy products: A review [PDF]

Food and Feed Research
Staphylococcus aureus is a highly adaptable microorganism that is commonly found in a variety of settings, including the skin and mucous membranes of humans and animals, as well as in the air, soil, and water.
Sinđić Milijana M., Nikolić Aleksandra V., Savić Radovanović Radoslava R., Grković Nevena N., Stajković Silvana S., Vićić Ivan N., Karabasil Neđeljko R.   +6 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Persistence survey of Toxic Shock Syndrome toxin-1 producing Staphylococcus aureus and serum antibodies to this superantigen in five groups of menstruating women

BMC Infectious Diseases, 2010
Background Menstrual Toxic Shock Syndrome (mTSS) is thought to be associated with the vaginal colonization with specific strains of Staphylococcus aureus TSST-1 in women who lack sufficient antibody titers to this toxin.
Parsonnet Jeffrey, Hansmann Melanie A, Seymour Jon L, Delaney Mary L, DuBois Andrea M, Modern Paul A, Jones Michaelle B, Wild John E, Onderdonk Andrew B   +8 more
doaj   +1 more source