Results 101 to 110 of about 2,950,586 (348)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Co-Formulants in Glyphosate-Based Herbicides Disrupt Aromatase Activity in Human Cells below Toxic Levels [PDF]

, 2016
Nicolas Defarge, Eszter Takács, Verónica Laura Lozano, Robin Mesnage, Joël Spiroux de Vendômois, Gilles-Éric Séralini, András Székács   +6 more
openalex   +1 more source

The financial burden and distress of patients with cancer: Understanding and stepping‐up action on the financial toxicity of cancer treatment

Ca, 2018
“Financial toxicity” has now become a familiar term used in the discussion of cancer drugs, and it is gaining traction in the literature given the high price of newer classes of therapies.
Pricivel M Carrera, H. Kantarjian, V. Blinder   +2 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Assessment of Lambda-Cyhalothrin and Spinetoram Toxicity and Their Effects on the Activities of Antioxidant Enzymes and Acetylcholinesterase in Honey Bee (Apis mellifera) Larvae

Insects
Honeybees play a crucial role as agricultural pollinators and are frequently exposed to various pollutants, including pesticides. In this study, we aimed to evaluate the toxicity of lambda-cyhalothrin (LCY) and spinetoram (SPI) in honey bee larvae reared
Ji-Yeong Choi, Kyongmi Chon, Juyeong Kim, Bala Murali Krishna Vasamsetti, Bo-Seon Kim, Chang-Young Yoon, Sojeong Hwang, Kyeong-Hun Park, Ji-Hoon Lee   +8 more
doaj   +1 more source

Evaluation of the Bioremediation Potential of Staphlococcus lentus Inoculations of Plants as a Promising Strategy Used to Attenuate Chromium Toxicity [PDF]

, 2022
Nuzhat Jamil, Sajjad Hyder, Mohammad Valipour, Muhammad Yasir, Rashid Iqbal, Rana Roy, Muhammad Umar Zafar, Ambreen Ahmed   +7 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Generation of induced pluripotent stem cell line UJSi005-A from developmentally delayed schizophrenic patients

Stem Cell Research
Schizophrenia, a chronic mental health condition, is characterized by abnormalities in perception, emotions and behavior. We successfully generated induced pluripotent stem cells (iPSCs) from the peripheral blood mononuclear cells (PBMCs) of a patient ...
Xuan Xu, Bing Xue, Dingqi Zhang, Yupeng Wang, Bonan Chen, Zhenghua Shan, Wenzhuo Zhao, Tianxiao Qiu, Jing Sun, Shengying Qin   +9 more
doaj   +1 more source

RNA toxicity in non‐coding repeat expansion disorders [PDF]

, 2019
Bart Swinnen, Wim Robberecht, Ludo Van Den Bosch   +2 more
openalex   +1 more source

Geochemical Fractionation and Risk Assessment of Potentially Toxic Elements in Sediments from Kupa River, Croatia [PDF]

, 2020
Sanja Sakan, Stanislav Frančišković-Bilinski, Dragana Đorđević, Aleksandar Popović, Sandra Škrivanj, Halka Bilinski   +5 more
openalex   +1 more source