Evaluation of mutagenicity of zinc oxide nanoparticles by Pig-a mutation assay in vivo
Shanghai yufang yixue, 2022 ObjectiveThe genotoxicity of zinc oxide nanoparticles （ZnO NPs） in rats was determined by Pig⁃a mutation assay in vivo.MethodsCombined with 28-day oral toxicity test， male SD rats were given ZnO NPs by oral administration for 28 days， at doses of 0， 14 ...
CHENG Xueqing +4 more
doaj +1 more source
Developmental Toxic Effects of Thiram on Developing Zebrafish (Danio rerio) Embryos
Toxics, 2022 Thiram, an oxidized dimer of dithiocarbamate, has fungicidal and ectoparasiticidal roles. This study aimed to determine the effects of thiram on the development of zebrafish (ZF) embryos.
Bala Murali Krishna Vasamsetti +5 more
doaj +1 more source
Acute and Subchronic Inhalation Toxicity of n-Octane in Rats
Safety and Health at Work, 2010 Objectives: We have investigated the toxic effects of the inhalation of subchronic and acute levels of n-octane. Methods: The rats were exposed to n-octane of 0, 2.34, 11.68 and 23.36 mg/L (n = 5 rats/group/gender) in an acute inhalation test ...
Jae Hyuck Sung +8 more
doaj +1 more source
Toxicity of Nanomaterials [PDF]
BioMed Research International, 2015 This decade has seen revolutionary developments in the field of nanotechnology with newer and diverse applications of nanoparticles (NPs) appearing every day. However, there are limited data about the toxicity of nanoparticles and their fate in biological systems.
Haseeb A. Khan, Rishi Shanker
openaire +3 more sources
Carboplatin/taxane-induced gastrointestinal toxicity: a pharmacogenomics study on the SCOTROC1 trial [PDF]
, 2016 Carboplatin/taxane combination is first-line therapy for ovarian cancer. However, patients can encounter treatment delays, impaired quality of life, even death because of chemotherapy-induced gastrointestinal (GI) toxicity.
Brown, R. +7 more
core +1 more source
Current Opinion in Neurology, 2014 Purpose of reviewOur aim is to highlight major advances reported in the last few years in drug-induced muscle toxicity.Recent findingsOur focus is on myopathies induced by statins and immune checkpoint inhibitors with a brief overview of rare steroid myopathies.
Mamatha, Pasnoor +2 more
openaire +3 more sources
Poison Frog Colors Are Honest Signals Of Toxicity, Particularly For Bird Predators [PDF]
, 2012 Antipredator defenses and warning signals typically evolve in concert. However, the extensive variation across taxa in both these components of predator deterrence and the relationship between them are poorly understood.
Cummings, Molly E., Maan, Martine E.
core +3 more sources
High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]
, 2013 BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Baltas, Dimos +6 more
core +1 more source
Toxics, 2023 The skin sensitization potential of agrochemicals can be assessed using laboratory methods such as the keratinocyte activation assay so that their use in regulatory toxicology might replace experimental animal testing.
Ji-Yeon Yang +6 more
doaj +1 more source
Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins. [PDF]
, 2011 Background - Bacillus thuringiensis Cry toxins are used worldwide in the control of different insect pests important in agriculture or in human health. The Cry proteins are pore-forming toxins that affect the midgut cell of target insects.
Bakker, P. +8 more
core +4 more sources