Results 11 to 20 of about 2,950,586 (348)
MedComm, 2023 Nanoparticles (NPs) have become one of the most popular objects of scientific study during the past decades. However, despite wealth of study reports, still there is a gap, particularly in health toxicology studies, underlying mechanisms, and related ...
Lihui Xuan +4 more
semanticscholar +1 more source
Journal of nanoparticle research, 2023 Rapidly growing interest in using nanoparticles (NPs) for biomedical applications has increased concerns about their safety and toxicity. In comparison with bulk materials, NPs are more chemically active and toxic due to the greater surface area and ...
Reza Abbasi +4 more
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Nanomaterials and nanoparticles: Sources and toxicity [PDF]
Biointerphases, 2007 This review is presented as a common foundation for scientists interested in nanoparticles, their origin, activity, and biological toxicity. It is written with the goal of rationalizing and informing public health concerns related to this sometimes ...
C. Buzea, I. Pacheco, K. Robbie
semanticscholar +1 more source
Biomedicines, 2022 Telomerase reactivation is responsible for telomere preservation in about 90% of cancers, providing cancer cells an indefinite proliferating potential.
Eric Nguyen +4 more
doaj +1 more source
Evaluation of mutagenicity of zinc oxide nanoparticles by Pig-a mutation assay in vivo
Shanghai yufang yixue, 2022 ObjectiveThe genotoxicity of zinc oxide nanoparticles （ZnO NPs） in rats was determined by Pig⁃a mutation assay in vivo.MethodsCombined with 28-day oral toxicity test， male SD rats were given ZnO NPs by oral administration for 28 days， at doses of 0， 14 ...
CHENG Xueqing +4 more
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Developmental Toxic Effects of Thiram on Developing Zebrafish (Danio rerio) Embryos
Toxics, 2022 Thiram, an oxidized dimer of dithiocarbamate, has fungicidal and ectoparasiticidal roles. This study aimed to determine the effects of thiram on the development of zebrafish (ZF) embryos.
Bala Murali Krishna Vasamsetti +5 more
doaj +1 more source
Journal of Medicinal Chemistry, 2015 Drug development has a high attrition rate, with poor pharmacokinetic and safety properties a significant hurdle. Computational approaches may help minimize these risks.
Douglas E. V. Pires +2 more
semanticscholar +1 more source
The Effects of Cadmium Toxicity
International Journal of Environmental Research and Public Health, 2020 Cadmium (Cd) is a toxic non-essential transition metal that poses a health risk for both humans and animals. It is naturally occurring in the environment as a pollutant that is derived from agricultural and industrial sources.
G. Genchi +4 more
semanticscholar +1 more source
Acute and Subchronic Inhalation Toxicity of n-Octane in Rats
Safety and Health at Work, 2010 Objectives: We have investigated the toxic effects of the inhalation of subchronic and acute levels of n-octane. Methods: The rats were exposed to n-octane of 0, 2.34, 11.68 and 23.36 mg/L (n = 5 rats/group/gender) in an acute inhalation test ...
Jae Hyuck Sung +8 more
doaj +1 more source
Immune-checkpoint inhibitors: long-term implications of toxicity
Nature Reviews Clinical Oncology, 2022 The development of immune-checkpoint inhibitors (ICIs) has heralded a new era in cancer treatment, enabling the possibility of long-term survival in patients with metastatic disease, and providing new therapeutic indications in earlier-stage settings. As
Douglas B. Johnson +3 more
semanticscholar +1 more source