Results 71 to 80 of about 780,751 (311)

Toxicity Test for the Extract of Symbiont Bacteria Bacillus sp. as Anti-bacteria [PDF]

open access: yes, 2019
Increased antibiotic resistance spurs exploration of bioactive compounds as new antibiotic alternatives. Bacillus sp. is a symbiont bacterium which is a marine microorganism that has the potential to produce new bioactive compounds that can be developed ...
Sulistiyani, Sulistiyani   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Toxicity evaluation and medical application of multi-walled carbon nanotubes [PDF]

open access: yes, 2015
Carbon nanotubes (CNTs) are of special interest to industry and they have been increasingly utilised as advanced nanovectors in drug/gene delivery systems.
Zhou, Lulu
core  

Signs of acute toxicity test.

open access: yes, 2014
Signs of acute toxicity test.
Dilnur Ahmat (532492)   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Investigating the change of planktonic communities (phytoplankton, zooplankton) in the water of Karun-4 lake in Chaharmahal and Bakhtiari province [PDF]

open access: yesبوم‌شناسی آبزیان
Lakes play a vital role in water conservation, biodiversity, tourism and job creation. However, seasonal changes, inflow of sewage and erosion increase the amount of nutrients discharged into the lakes and affect the structure of the ecosystem and the ...
Ruhollah Rahimi   +4 more
doaj  

A 4-Week, Repeated, Intravenous Dose, Toxicity Test of Mountain Ginseng Pharmacopuncture in Sprague-Dawley Rats

open access: yesJournal of Pharmacopuncture, 2014
Objectives: Mountain ginseng pharmacopuncture (MGP) is a pharmacopuncture made by distilling extract from mountain cultivated ginseng or mountain wild ginseng.
Kwangho Lee   +4 more
doaj   +1 more source

O peixe zebra como uma ferramenta para avaliação de ecotoxicidade

open access: yes, 2009
Mestrado em Toxicologia e EcotoxicologiaO peixe-zebra (Danio rerio) é um vertebrado modelo grandemente utilizado em investigação científica em todo o mundo.
Oliveira, Rhaul
core  

Understanding the causes of toxicity in treated landfill leachate through whole eefluent testing [PDF]

open access: yes, 2010
Landfill leachate is collected and treated before discharge to protect the environment from a potential toxic cocktail of substances. In the U.K. biological treatment is the favourite technology for rendering landfill leachate safe due its simple ...
Thomas, David J. L.
core  

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