Results 71 to 80 of about 742,766 (263)

Does selenium offset methylmercury toxicity across trophic levels in a primary producer, Auxenochlorella pyrenoidosa, and a detritovore, Aeolosoma variegatum?

open access: yesFACETS
Methylmercury ([CH3Hg]+ or MeHg) is a potent neurotoxin that impairs functioning of the nervous system, and selenium (Se) is known to provide a protective effect against MeHg.
Husnah Azmi   +2 more
doaj   +1 more source

Intravenous Single Dose Toxicity of Sweet Bee Venom in Sprague-Dawley Rats

open access: yesJournal of Pharmacopuncture, 2015
Objectives: Anaphylactic shock can be fatal to people who become hypersensitive when bee venom pharmacopuncture (BVP) is used. Thus, sweet bee venom (SBV) was developed to reduce these allergic responses.
Kwang-Ho Lee   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

OF SODIUM NITRITE FOR SPINY-CHEEK CRAYFISH (ORCONECTES LIMOSUS RAF.) THE EFFECT OF CHLORIDE CONTENT IN WATER ON THE TOXICITY

open access: yesKnowledge and Management of Aquatic Ecosystems, 2005
Toxicity of sodium nitrite for the spiny-cheek crayfish (Orconectes limosus) was assessed in relation to the concentration of chlorides diluted in water.
KOZÁK P., MÁCHOVÁ J., POLICAR T.
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Single Intravenous-dose Toxicity of Water-soluble Carthami-flos Pharmacopuncture (WCF) in Rats

open access: yesJournal of Pharmacopuncture, 2014
Objectives: This study was performed to analyze the toxicity and to find the lethal dose of the test substance Water-soluble Carthami-flos pharmacopuncture (WCF) when used as a single intravenous-dose in 6-week-old, male and female Sprague-Dawley rats ...
Da-jung Jung   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Computational Design, Molecular Docking Study and Toxicity Prediction of Some Novel Pralidoxime Derivatives as reactivators of acetyl cholinesterase enzyme [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2019
Background & Objective: oximes as Acetylcholinesterase (AChE) reactivators were developed for the treatment of organophosphate compounds (OPCs) intoxication.
abozar roeintan
doaj  

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