Results 1 to 10 of about 814,677 (243)

The evolving role of investigative toxicology in the pharmaceutical industry

open access: yesNature reviews. Drug discovery, 2023
For decades, preclinical toxicology was essentially a descriptive discipline in which treatment-related effects were carefully reported and used as a basis to calculate safety margins for drug candidates.
F. Pognan   +13 more
semanticscholar   +1 more source

The Role of Cytochrome P450s in Insect Toxicology and Resistance.

open access: yesAnnual Review of Entomology, 2021
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important physiological functions, but it is their role in the detoxification of xenobiotics, such as natural and synthetic insecticides, that is the topic of this review. Recent advances
R. Nauen   +3 more
semanticscholar   +1 more source

The Current State of Veterinary Toxicology Education at AAVMC Member Veterinary Schools

open access: yesVeterinary Sciences, 2022
This study assessed the depth, breadth, and perception of toxicology education in curricula at Association of American Veterinary Medical Colleges (AAVMC) member veterinary schools.
David C. Dorman   +2 more
doaj   +1 more source

North American Congress of Clinical Toxicology (NACCT) 2022

open access: yesClinical toxicology, 2022
Background: The Coronavirus disease 2019 pandemic led to unprecedented changes to medical education as educators adapted to a world necessitating precautions and social distancing.
N. Titelbaum   +3 more
semanticscholar   +1 more source

Positive Toxicology Results Are Not Associated with Emergency Physicians’ Opioid Prescribing Behavior

open access: yesWestern Journal of Emergency Medicine, 2021
Introduction: Given the general lack of literature on opioid and naloxone prescribing guidelines for patients with substance use disorder, we aimed to explore how a physician’s behavior and prescribing habits are altered by knowledge of the patient’s ...
Jonathan B. Lee   +7 more
doaj   +1 more source

Casting a wide net: use of diverse model organisms to advance toxicology [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hahn, M. E., & Sadler, K. C. Casting a wide net: use of diverse model organisms to advance toxicology.
Hahn, Mark E., Sadler, Kirsten C.
core   +1 more source

Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology

open access: yesMolecules, 2020
Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. The term “nanoparticle” stands for both nanocapsules and nanospheres,
A. Zielińska   +11 more
semanticscholar   +1 more source

Toxicology and pharmacology of synthetic organoselenium compounds: an update

open access: yesArchives of Toxicology, 2021
Here, we addressed the pharmacology and toxicology of synthetic organoselenium compounds and some naturally occurring organoselenium amino acids. The use of selenium as a tool in organic synthesis and as a pharmacological agent goes back to the middle of
C. W. Nogueira, N. V. Barbosa, J. Rocha
semanticscholar   +1 more source

An Unusually High Blood Alcohol Level in a Burnt Child Homicide Victim [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2019
Background: Alcohol detection is one of the most prevalent requests in forensic toxicology laboratories for medico-legal investigation. Interpretation of analytical toxicology results is important in deciding the cause and manner of death.
Masoud Ghadipasha, Maryam Akhgari
doaj   +1 more source

Nickel: Human Health and Environmental Toxicology

open access: yesInternational Journal of Environmental Research and Public Health, 2020
Nickel is a transition element extensively distributed in the environment, air, water, and soil. It may derive from natural sources and anthropogenic activity.
G. Genchi   +4 more
semanticscholar   +1 more source

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